Publication: Serum antibody responses in opisthorchiasis
Issued Date
1995-01-01
Resource Type
ISSN
00207519
Other identifier(s)
2-s2.0-0029132193
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal for Parasitology. Vol.25, No.8 (1995), 971-973
Suggested Citation
P. S. Akai, S. Pungpak, W. Chaicumpa, V. Kitikoon, Y. Ruangkunaporn, D. Bunnag, A. D. Befus Serum antibody responses in opisthorchiasis. International Journal for Parasitology. Vol.25, No.8 (1995), 971-973. doi:10.1016/0020-7519(94)00212-7 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/17310
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Title
Serum antibody responses in opisthorchiasis
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Abstract
We evaluated an enzyme-linked immunosorbent assay using crude parasite homogenates as a diagnostic test for Opisthorchis viverrini infection in humans. Serum antibody (Ab) responses to O. viverrini adult worm homogenate (AWH) and metacercaria homogenate (MH) were studied in 83 infected residents of an opisthorchiasis-endemic area in Thailand. Elevated levels of Ab persisted for over 1 year following curative treatment with praziquantel, and cross-reactivity to O. viverrini AWH and MH antigens was observed in sera from individuals with other parasitic infections. Serum Ab to crude AWH and MH are therefore unsuitable for immunodiagnosis since they may be non-specific and would not differentiate between ongoing and past infection. © 1995.