Publication: Cytotoxic alkaloids from leaves and twigs of Dasymaschalon sootepense
| dc.contributor.author | Sakchai Hongthong | en_US |
| dc.contributor.author | Chutima Kuhakarn | en_US |
| dc.contributor.author | Vichai Reutrakul | en_US |
| dc.contributor.author | Surawat Jariyawat | en_US |
| dc.contributor.author | Pawinee Piyachaturawat | en_US |
| dc.contributor.author | Narong Nuntasaen | en_US |
| dc.contributor.author | Thaworn Jaipetch | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | National Park, Wildlife and Plant Conservation Department, Thailand | en_US |
| dc.date.accessioned | 2018-11-09T01:48:05Z | |
| dc.date.available | 2018-11-09T01:48:05Z | |
| dc.date.issued | 2014-01-01 | en_US |
| dc.description.abstract | Bioassay-guided fractionation of the cytotoxic ethyl acetate fraction of the sequential methanol extract from the leaves and twigs of Dasymaschalon sootepense led to the isolation of a new 7-hydroxy aporphine alkaloid, 6a,7-dehydrodasymachaline (1) along with the five known compounds (-)-nordicentrine (2), dicentrinone (3), (-)-sinactine (4), aristolactam AII (5) and epiberberine (6). Their structures were elucidated by spectroscopic methods. This is the first report of alkaloids 1-2 and 5-6 from the genus Dasymaschalon. Compounds 1 and 5 showed cytotoxicity against a panel of cancer cell lines. | en_US |
| dc.identifier.citation | Natural Product Communications. Vol.9, No.7 (2014), 929-932 | en_US |
| dc.identifier.issn | 15559475 | en_US |
| dc.identifier.issn | 1934578X | en_US |
| dc.identifier.other | 2-s2.0-84905110963 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/33151 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84905110963&origin=inward | en_US |
| dc.subject | Agricultural and Biological Sciences | en_US |
| dc.subject | Medicine | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Cytotoxic alkaloids from leaves and twigs of Dasymaschalon sootepense | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84905110963&origin=inward | en_US |