Detection of shared antigens of human liver flukes Opisthorchis viverrini and its snail host, Bithynia spp.

Abstract

The relationship between Opisthorchis viverrini and its snail intermediate host including Bithynia funiculata, B. siamensis and B. siamensis goniomphalos was carried out on the correction of shared antigens and infection rates. B. funiculata and B. s. siamensis were equally susceptible to O. viverrini with relatively high infection rates of 72.2% and 69.9% respectively whereas B. s. goniomphalos gave lowest percentage of infection of only 9.6%. By immunoelectrophoresis, crude extract of O. viverrini adult worm produced the same number of two common precipitin bands of four different electrophoretic mobilities against anti-B. funiculata and anti-B. s. siamensis sera and one precipitin band in the antigen well region against anti-B. s. goniomphalos serum. The three snail antigens produced the same number of two common precipitin bands against anti-O. viverrini serum.