Publication: Prevalence and risk factors of acquiring Strongyloides stercoralis infection among patients attending a tertiary hospital in Thailand
3
Issued Date
2014-01-01
Resource Type
ISSN
20477732
20477724
20477724
Other identifier(s)
2-s2.0-84899622398
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Pathogens and Global Health. Vol.108, No.3 (2014), 137-140
Suggested Citation
Ubonvan Jongwutiwes, Duangdao Waywa, Saowaluk Silpasakorn, Darawan Wanachiwanawin, Yupin Suputtamongkol Prevalence and risk factors of acquiring Strongyloides stercoralis infection among patients attending a tertiary hospital in Thailand. Pathogens and Global Health. Vol.108, No.3 (2014), 137-140. doi:10.1179/2047773214Y.0000000134 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/34045
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Prevalence and risk factors of acquiring Strongyloides stercoralis infection among patients attending a tertiary hospital in Thailand
Other Contributor(s)
Abstract
Objectives: We aimed to determine the prevalence and risk factors for Strongyloides stercoralis infection in adult patients attending Siriraj Hospital, a tertiary hospital in Thailand. Methods: A case-control study was carried out between July 2008 and April 2010. Case and control were identified from 6022 patients for whom results of faecal examination were available. A case was a patient who had S. stercoralis larva detected from faecal examination. Control was randomly selected from patients without S. stercoralis larvae detected in three consecutive faecal examinations. The proportion of control to case was 2: 1. Demographic and clinical data for the day of diagnosis and retrospectively up to 15 days preceding the date of faecal examination were reviewed from their medical records. Results: Overall, 149 (2.47%) patients had S. stercoralis larvae positive. There were 105 males (70.5%), with the mean (SD) age of 53.9 (17.2) years. A total of 300 controls were selected. Male gender (odds ratio (OR) 5 2.79, 95% confidence interval (CI) 1.78-4.27)), human immunodeficiency virus (HIV) infection (OR 5 3.23, 95% CI 1.43-7.29), and eosinophilia (OR 5 1.81, 95% CI 1.33-2.47) were found to be independent risk factors associated with S. stercoralis infection in this setting. Corticosteroid or other immunosuppressive treatment, and other concomitant illnesses were not associated with increased risk of S. stercoralis infection. Conclusion: In this setting, strongyloidiasis was seen more often in male patients with eosinophilia and with HIV infection. Prevention of fatal complication caused by S. stercoralis by regular faecal examination, or serology for early detection and treatment of undiagnosed S. stercoralis infection, is warranted in these high-risk patients. © W. S. Maney & Son Ltd 2014.