Publication:
Histologic types of breast carcinoma in relation to international variation and breast cancer risk factors

Issued Date

1989-01-01

Resource Type

Article

ISSN

10970215
00207136

DOI

10.1002/ijc.2910440304

Other identifier(s)

2-s2.0-0024443956

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

International Journal of Cancer. Vol.44, No.3 (1989), 399-409

Suggested Citation

H. Stalsberg, D. B. Thomas, E. A. Noonan, G. Berry, R. Maclennan, R. Shearman, T. Jelihovsky, J. Cooper Booth, R. Molina, L. Martinez, O. Salas, A. Dabancens, Chen Zhiheng, Tao Yun, Hu Yong Wei, A. Cuadros, N. Aristizabal, K. Ebeling, P. Nishan, D. Kunde, B. Modan, E. Ron, E. Alfandary, J. G. Mati, P. Kenya, A. Kungu, D. Gatei, H. Rodriguez Cuevas, S. Benavides Salazar, A. Palet, P. Ontiveros, R. A. Apelo, J. R.La De Cruz, J. Baens, B. Javier, Suporn Silpisornkosol, Tieng Pardthaisong, Nimit Martin, Choti Theetranont, Banpot Boosiri, Supawat Chutivongse, Pramuan Virutamasen, Chansuda Wongsrichanalai, Prasarn Jimakorn, Suporn Koetsawang, Daungdao Rachawat, Nivat Chantarakul, S. Holck Histologic types of breast carcinoma in relation to international variation and breast cancer risk factors. International Journal of Cancer. Vol.44, No.3 (1989), 399-409. doi:10.1002/ijc.2910440304 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15734

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Thesis

Title

Histologic types of breast carcinoma in relation to international variation and breast cancer risk factors

Author(s)

H. Stalsberg
 D. B. Thomas
 E. A. Noonan
 G. Berry
 R. Maclennan
 R. Shearman
 T. Jelihovsky
 J. Cooper Booth
 R. Molina
 L. Martinez
 O. Salas
 A. Dabancens
 Chen Zhiheng
 Tao Yun
 Hu Yong Wei
 A. Cuadros
 N. Aristizabal
 K. Ebeling
 P. Nishan
 D. Kunde
 B. Modan
 E. Ron
 E. Alfandary
 J. G. Mati
 P. Kenya
 A. Kungu
 D. Gatei
 H. Rodriguez Cuevas
 S. Benavides Salazar
 A. Palet
 P. Ontiveros
 R. A. Apelo
 J. R.La De Cruz
 J. Baens
 B. Javier
 Suporn Silpisornkosol
 Tieng Pardthaisong
 Nimit Martin
 Choti Theetranont
 Banpot Boosiri
 Supawat Chutivongse
 Pramuan Virutamasen
 Chansuda Wongsrichanalai
 Prasarn Jimakorn
 Suporn Koetsawang
 Daungdao Rachawat
 Nivat Chantarakul
 S. Holck

Other Contributor(s)

Universitetet i Tromso
 Fred Hutchinson Cancer Research Center
 The University of Sydney
 Facultad de Medicina de la Universidad de Chile
 Shanghai Institute of Planned Parenthood Research
 Hospital Universitario
 Academy of Sciences
 Chaim Sheba Medical Center Israel
 University of Nairobi
 Hospital General de Mexico
 University of the Philippines Manila
 Chiang Mai University
 Chulalongkorn University
 Mahidol University
 Organisation Mondiale de la Sante
 Development and Research Training in Human Reproduction

Abstract

Associations between breast cancer risk factors and histologic types of invasive breast carcinoma were studied in 2,728 patients. Lobular and tubular carcinomas occurred with increased relative frequency in most high‐risk groups. The proportion of these types increased with age to a maximum at 45–49 years and decreased in the following decade. Significantly increased proportions of lobular and tubular carcinomas were also associated with high‐risk countries, prior benign breast biopsy, bilateral breast cancer, concurrent mammary dysplasia, high age at first live birth, never‐pregnant patients compared to those with a first live birth before age 20, private pay status, and length of education. Nonsignificant increases were associated with family history of breast cancer, less than 5 live births, less than 25 months total of breast feeding, use of oral contraceptives or IUD, and high occupational class. As a general trend, the higher the overall relative risk, the higher the proportion of lobular and tubular carcinomas. The occurrence of other histologic types also increased with increased breast cancer risk, but to a smaller degree than for lobular/tubular carcinomas. It is suggested that all hormonally related, socio‐economic and geographic risk factors exert their effect by selectively increasing the number of lobular cells at risk. Family history of breast cancer and age over 49 years did not follow the general trend of parallel increases in the proportion of lobular/tubular carcinomas and breast cancer risk, and may operate through other mechanisms. Copyright © 1989 Wiley‐Liss, Inc., A Wiley Company

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/15734

Collections

Scopus 1969-1990