Publication:
TBAI/TBHP-Mediated Cascade Cyclization toward Sulfonylated Indeno[1,2-c]quinolines

Issued Date

2017-12-15

Resource Type

Article

ISSN

15237052
15237060

DOI

10.1021/acs.orglett.7b03246

Other identifier(s)

2-s2.0-85038411952

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Organic Letters. Vol.19, No.24 (2017), 6546-6549

Suggested Citation

Jatuporn Meesin, Manat Pohmakotr, Vichai Reutrakul, Darunee Soorukram, Pawaret Leowanawat, Saowanit Saithong, Chutima Kuhakarn TBAI/TBHP-Mediated Cascade Cyclization toward Sulfonylated Indeno[1,2-c]quinolines. Organic Letters. Vol.19, No.24 (2017), 6546-6549. doi:10.1021/acs.orglett.7b03246 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/41727

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Title

TBAI/TBHP-Mediated Cascade Cyclization toward Sulfonylated Indeno[1,2-c]quinolines

Author(s)

Jatuporn Meesin
 Manat Pohmakotr
 Vichai Reutrakul
 Darunee Soorukram
 Pawaret Leowanawat
 Saowanit Saithong
 Chutima Kuhakarn

Other Contributor(s)

Mahidol University
 Prince of Songkla University

Abstract

© 2017 American Chemical Society. Treatment of ortho-amino-substituted aryldiyne derivatives with sulfonyl hydrazides in the presence of tetrabutylammonium iodide (TBAI) and tert-butyl hydroperoxide (TBHP) led to a cascade cyclization reaction to yield sulfonylated indeno[1,2-c]quinolines in moderate to good yields. The features of the methodology include metal-free reaction, the ease of reagent handling, and a broad functional group tolerance.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/41727

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Scopus 2016-2017