Publication: Correlation between aortic stiffness and left atrial volume index in hypertensive patients
Issued Date
2016-02-17
Resource Type
ISSN
15256006
10641963
10641963
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2-s2.0-84959451988
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Mahidol University
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SCOPUS
Bibliographic Citation
Clinical and Experimental Hypertension. Vol.38, No.2 (2016), 160-165
Suggested Citation
Satit Janwanishstaporn, Thananya Boonyasirinant Correlation between aortic stiffness and left atrial volume index in hypertensive patients. Clinical and Experimental Hypertension. Vol.38, No.2 (2016), 160-165. doi:10.3109/10641963.2015.1081211 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/43087
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Title
Correlation between aortic stiffness and left atrial volume index in hypertensive patients
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Abstract
© 2016 Taylor & Francis Group, LLC. Background: Both arterial stiffness and left atrial volume index are crucial predictors of cardiovascular outcomes in hypertensive patients. The correlation between these two factors has not been previously well established in hypertensive population. Objectives: To determine the correlation between arterial stiffness and left atrial volume index in hypertensive patients. Methods and results: The study was performed in 111 consecutive hypertensive patients (49.5% male, mean age 70.8 ± 10.3 years) undergoing cardiac magnetic resonance imaging (CMR). Arterial stiffness was determined by pulse wave velocity in the thoracic aorta by velocity-encoded imaging. Left atrial volume was assessed by biplane area-length method. Pulse wave velocity was significantly correlated with left atrial volume index in univariate analysis (r = 0.20, p = 0.032). In multivariate analysis, pulse wave velocity, coronary artery disease and left ventricular mass remain independent predictors (β = 1.01, p = 0.02). Conclusion: Increased arterial stiffness correlates with left atrial enlargement in hypertensive patients. The prevention of left atrial enlargement and subsequent complications by specific antihypertensive drugs with positive effect on aortic stiffness warrants further studies.