Publication: A new ellagic acid from the leaves and twigs of irvingia malayana
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Issued Date
2019-05-01
Resource Type
ISSN
15559475
1934578X
1934578X
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2-s2.0-85066399165
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Mahidol University
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SCOPUS
Bibliographic Citation
Natural Product Communications. Vol.14, No.5 (2019)
Suggested Citation
Thaworn Jaipetch, Sakchai Hongthong, Samreang Bunteang, Radeekorn Akkarawongsapat, Jitra Limthongkul, Chanita Napaswad, Kanoknetr Suksen, Narong Nuntasaen, Vichai Reutrakul, Chutima Kuhakarn A new ellagic acid from the leaves and twigs of irvingia malayana. Natural Product Communications. Vol.14, No.5 (2019). doi:10.1177/1934578X19848164 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/49772
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Title
A new ellagic acid from the leaves and twigs of irvingia malayana
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Abstract
© The Author(s) 2019 A phytochemical investigation of the leaves and twigs of Irvingia malayana led to the isolation of a new 3,3′,4′-tri-O-methylellag-ic acid-6″-acetoxy-4-O-β-glucoside (1), along with 3,3′,4′-tri-O-methylellagic acid (2), 3,3′-di-O-methylellagic acid-4-O-β-xylo-side (3), 3,3′,4′-tri-O-methylellagic acid-4-β-O-glucoside (4), friedelin (5), friedelinol (6), methyl-3,4,5-trihydroxybenzoate (7), 5,7,4′-trihydroxyflavone-8-C-β-glucopyranoside (8), 5,7,3′,4′-tetrahydroxyflavone-8-C-β-glucopyranoside (9), and 5,3′,4′-tri-hydroxyflavone-6-C-β-glucopyranoside (10). Their structures were elucidated by means of spectroscopic techniques and direct comparison with literature data. Compounds 4 and 7 showed weak cytotoxic activity against a panel of mammalian cancerous cell lines. Furthermore, compounds 1, 2, 4, and 9 exhibited significant inhibitory activity in the syncytium inhibition assay, whereas compounds 8 and 9 displayed moderate activity in the HIV 1 reverse transcriptase assay.