Publication: Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases.
Issued Date
2006-06-01
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ISSN
00234001
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2-s2.0-39049182901
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Mahidol University
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SCOPUS
Bibliographic Citation
The Korean journal of parasitology. Vol.44, No.2 (2006), 139-143
Suggested Citation
Vipa Thanachartwet, Srivicha Krudsood, Polrat Wilairatana, Weerapong Phumratanaprapin, Udomsak Silachamroon, Sornchai Looareesuwan Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases.. The Korean journal of parasitology. Vol.44, No.2 (2006), 139-143. doi:10.3347/kjp.2006.44.2.139 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23325
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Title
Peripheral gangrene in patients with severe falciparum malaria: report of 3 cases.
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Abstract
Peripheral gangrene, characterized by distal ischemia of the extremities, is a rare complication in patients with falciparum malaria. Patients with this complication have generally undergone early amputation of the affected areas. In this report, we describe 3 adult Thai patients presented at the Hospital for Tropical Diseases, Bangkok, with high grade of fever ranged 6-9 days, jaundice, acute renal failure, respiratory failure, alteration of consciousness and shock. Two patients had gangrene developed at the lower extremities on day 1 of hospitalization and 1 patient had gangrene developed on day 3. Blood smears revealed hyperparasitemia with Plasmodium falciparum. These patients were diagnosed as having severe malaria with peripheral gangrene. The resolution of gangrene was successfully achieved by treatment with artesunate and conservative treatment in 2 of 3 cases.