Journal of the Medical Association of Thailand. Vol.84, No.SUPPL. 2 (2001)
Suggested Citation
Narong Bunyaratavej, Kaiming Chan, Narainswani Subramanian Treatment of painful osteoarthritis of the knee with hyaluronic acid results of a multicenter Asian study. Journal of the Medical Association of Thailand. Vol.84, No.SUPPL. 2 (2001). Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/26710
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Treatment of painful osteoarthritis of the knee with hyaluronic acid results of a multicenter Asian study
Hyaluronic acid is a component of synovial fluid, in osteoarthritis (OA) and shows a change of property of hyaluronic acid especially its viscoelasticity causing degradation of the cartilage. Injection of hyaluronic acid into OA of the knee (Hyalgan® 2 ml/wk for 4 doses) in international multicentres gave dramatic responses : decreased pain, increased mobility of the joint after 49 days of injections compared to a placebo (2 ml of normal saline) p<0.01.