Publication: Tropical oil consumption and cardiovascular disease: An umbrella review of systematic reviews and meta analyses
5
Issued Date
2021-05-01
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ISSN
20726643
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2-s2.0-85105146118
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Mahidol University
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SCOPUS
Bibliographic Citation
Nutrients. Vol.13, No.5 (2021)
Suggested Citation
Chanita Unhapipatpong, Prapimporn Chattranukulchai Shantavasinkul, Vijj Kasemsup, Sukanya Siriyotha, Daruneewan Warodomwichit, Sirikan Maneesuwannarat, Prin Vathesatogkit, Piyamitr Sritara, Ammarin Thakkinstian Tropical oil consumption and cardiovascular disease: An umbrella review of systematic reviews and meta analyses. Nutrients. Vol.13, No.5 (2021). doi:10.3390/nu13051549 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/75675
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Title
Tropical oil consumption and cardiovascular disease: An umbrella review of systematic reviews and meta analyses
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Abstract
The health effects of saturated fat, particularly tropical oil, on cardiovascular disease are unclear. We investigated the effect of tropical oil (palm and coconut oils), lard, and other common vegetable oils (soybean and rice bran oils) that are widely used in tropical and Asian countries on lipid profiles. We performed an umbrella review of meta-analyses and systematic reviews. Electronic databases (Medline, Scopus, Embase, and Cochrane) were searched up to December 2018 without language restriction. We identified nine meta-analyses that investigated the effect of dietary oils on lipid levels. Replacement of polyunsaturated fatty-acid-rich oils (PUFAs) and monounsaturated FA-rich oils (MUFAs) with palm oil significantly increased low-density lipoprotein cholesterol (LDL-c), by 3.43 (0.44–6.41) mg/dL and 9.18 (6.90–11.45) mg/dL, respectively, and high-density lipoprotein cholesterol (HDL-c), by 1.89 (1.23–2.55) mg/dL and 0.94 (−0.07–1.97) mg/dL, respectively. Replacement of PUFAs with coconut oil significantly increased HDL-c and total cholesterol –by 2.27 (0.93–3.6) mg/dL and 5.88 (0.21–11.55) mg/dL, respectively—but not LDL-c. Substituting lard for MUFAs and PUFAs increased LDL-c–by 8.39 (2.83–13.95) mg/dL and 9.85 (6.06–13.65) mg/dL, respectively—but not HDL-c. Soybean oil substituted for other PUFAs had no effect on lipid levels, while rice bran oil substitution decreased LDL-c. Our findings show the deleterious effect of saturated fats from animal sources on lipid profiles. Replacement of unsaturated plant-derived fats with plant-derived saturated fats slightly increases LDL-c but also increases HDL-c, which in turn may exert a neutral effect on cardiovascular health.