Publication: Cutaneous reactions to non-steroidal anti-inflammatory drugs
Issued Date
2011-10-01
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ISSN
15459616
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2-s2.0-80054767738
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Drugs in Dermatology. Vol.10, No.10 (2011), 1160-1167
Suggested Citation
Pranee Kasemsarn, Kanokvalai Kulthanan, Papapit Tuchinda, Naruemon Dhana, Kowit Jongjarearnprasert Cutaneous reactions to non-steroidal anti-inflammatory drugs. Journal of Drugs in Dermatology. Vol.10, No.10 (2011), 1160-1167. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/12280
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Title
Cutaneous reactions to non-steroidal anti-inflammatory drugs
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Abstract
We retrospectively reviewed the records of 195 patients with suspected cutaneous reactions from NSAIDs. Two hundred and six different non-steroidal anti-inflammatory drugs (NSAIDs) were suspected of causing cutaneous reactions, and the most frequent suspected causative NSAID was ibuprofen (25.7%). Angioedema and/or urticaria were the most frequent cutaneous reactions (54.4%), and the foremost suspected causative drug for these reactions was ibuprofen. The second most frequently found cutaneous reaction was maculopapular eruption (26.2%), and celecoxib was the most commonly suspected causative NSAID for it. The primary suspected NSAIDs causing fixed drug eruption were in enolic acid group. Furthermore, drug hypersensitivity syndrome was diagnosed in five patients, and Stevens-Johnson syndrome and toxic epidermal necrolysis were detected in five patients. Copyright © 2011 Journal of Drugs in Dermatology.