Publication: Asymptomatic Histoplasma Pylephlebitis in an Orthotopic Liver Transplant Recipient: A Case Report and Literature Review
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Issued Date
2019-02-15
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ISSN
15730832
0301486X
0301486X
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2-s2.0-85061268163
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Mahidol University
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SCOPUS
Bibliographic Citation
Mycopathologia. Vol.184, No.1 (2019), 177-180
Suggested Citation
Pakpoom Phoompoung, Methee Chayakulkeeree, Popchai Ngamskulrungroj, Ananya Pongpaibul Asymptomatic Histoplasma Pylephlebitis in an Orthotopic Liver Transplant Recipient: A Case Report and Literature Review. Mycopathologia. Vol.184, No.1 (2019), 177-180. doi:10.1007/s11046-018-0265-6 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/49811
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Title
Asymptomatic Histoplasma Pylephlebitis in an Orthotopic Liver Transplant Recipient: A Case Report and Literature Review
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Abstract
© 2018, Springer Science+Business Media B.V., part of Springer Nature. Histoplasma capsulatum is one of the most common pathogenic dimorphic fungi in Thailand. Its usual clinical syndrome is progressive disseminated histoplasmosis, whereas isolated hepatic histoplasmosis is extremely rare. Here, we report the world’s first reported case of hepatic histoplasmosis with pylephlebitis in a 45-year-old Thai male who underwent orthotopic liver transplantation due to hepatitis B cirrhosis. Histopathology of the recipient’s liver showed infiltration of fungal organisms in portal vein and hepatic granulomas. Serum H. capsulatum antibody was positive, and molecular identification from the liver revealed the DNA of H. capsulatum.