Publication: Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritis
Issued Date
2000-06-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0034201621
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.2 (2000), 335-338
Suggested Citation
Saowanee Kajanachumpol, Monchand Vanichapuntu, Oravan Verasertniyom, Kitti Totemchokchyakarn, Mongkol Vatanasuk Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritis. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.31, No.2 (2000), 335-338. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/26228
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Title
Levels of plasma lipid peroxide products and antioxidant status in rheumatoid arthritis
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Abstract
Oxygen free radicals have been implicated as mediators of tissue damage in patients with rheumatoid arthritis. The aim of our study was to assess the lipid peroxide products and antioxidant status in rheumatoid arthritis patients (RA). The study involved determination of two plasma lipid peroxide products, malondialdehyde (MDA) and conjugated dienes (CD), two plasma antioxidant vitamins (C and E) in 91 RA patients and 26 healthy subjects. The results showed that rheumatoid patients had increased plasma CD but not MDA and decreased plasma vitamin E, when properly expressed per unit cholesterol and triglyceride. This finding suggested that RA patients had increased oxidant stress that might play a role in the tissue damage and inflammation process of this disease.