Publication: Association of infant feeding practices with iron status and hematologic parameters in 6-month-old infants
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Issued Date
2021-12-01
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ISSN
22279067
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2-s2.0-85121821241
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Mahidol University
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SCOPUS
Bibliographic Citation
Children. Vol.8, No.12 (2021)
Suggested Citation
Chayatat Ruangkit, Nawapat Prachakittikul, Nutthida Hemprachitchai, Oraporn Dumrongwongsiri, Sasivimon Soonsawad Association of infant feeding practices with iron status and hematologic parameters in 6-month-old infants. Children. Vol.8, No.12 (2021). doi:10.3390/children8121159 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/77453
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Title
Association of infant feeding practices with iron status and hematologic parameters in 6-month-old infants
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Abstract
Background: Infants’ feeding practices in the first 6 months of life and their association with iron status and hematologic parameters has not been well studied. We aim to evaluate this association. Methods: In a retrospective chart review, we identified 403 infants who received laboratory screening for anemia at 6-month visits. Infants were categorized into four groups according to feeding practices. Hematologic parameters and incidence of anemia, iron deficiency (ID), and iron deficiency anemia (IDA) were compared. Results: In total, 105 infants were breastfed (BF), 78 were breastfed with iron supplementation starting at 4 months (BI), 109 were mixed-fed (breast milk and formula) with or without iron supplementation (MF), and 111 were formula-fed (FF). The BF group had the highest incidence of anemia (38.1%), ID (28.6%), and IDA (17.1%) when compared with the other groups (p < 0.001). In multivariate logistic regression, BI, MF, and FF infants had 90.4%, 97.5%, and 96.9% decreased risk of IDA, respectively, with BF infants as a reference group. Conclusion: The incidence of anemia, ID, and IDA at age 6 months was higher in BF than FF or MF infants. However, iron supplements in BF infants starting at 4 months significantly reduced their ID and IDA incidence.