Publication: Socio-economic status and risk of tuberculosis: A case-control study of HIV-infected patients in Asia
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Issued Date
2018-02-01
Resource Type
ISSN
18157920
10273719
10273719
Other identifier(s)
2-s2.0-85040794973
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Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
International Journal of Tuberculosis and Lung Disease. Vol.22, No.2 (2018), 179-186
Suggested Citation
A. Jiamsakul, M. P. Lee, K. V. Nguyen, T. P. Merati, D. D. Cuong, R. Ditangco, E. Yunihastuti, S. Ponnampalavanar, F. Zhang, S. Kiertiburanakul, A. Avihingasanon, O. T. Ng, B. L.H. Sim, W. W. Wong, J. Ross, M. Law Socio-economic status and risk of tuberculosis: A case-control study of HIV-infected patients in Asia. International Journal of Tuberculosis and Lung Disease. Vol.22, No.2 (2018), 179-186. doi:10.5588/ijtld.17.0348 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/46990
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Title
Socio-economic status and risk of tuberculosis: A case-control study of HIV-infected patients in Asia
Other Contributor(s)
Hospital Sungai Buloh
Beijing Ditan Hospital
Gokila
Bach Mai Hospital
Universitas Udayana
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
University of Malaya
Chulalongkorn University
Kirby Institute
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Queen Elizabeth Hospital Hong Kong
Veterans General Hospital-Taipei
Tan Tock Seng Hospital
National Hospital for Tropical Diseases
amfAR - The Foundation for AIDS Research
Beijing Ditan Hospital
Gokila
Bach Mai Hospital
Universitas Udayana
University of Indonesia, RSUPN Dr. Cipto Mangunkusumo
University of Malaya
Chulalongkorn University
Kirby Institute
Faculty of Medicine, Ramathibodi Hospital, Mahidol University
Queen Elizabeth Hospital Hong Kong
Veterans General Hospital-Taipei
Tan Tock Seng Hospital
National Hospital for Tropical Diseases
amfAR - The Foundation for AIDS Research
Abstract
© 2018 The Union. SETTING: Tuberculosis (TB) is the most common human immunodeficiency virus (HIV) related opportunistic infection and cause of acquired immune-deficiency syndrome related death. TB often affects those from a low socio-economic background. OBJECTIVE : To assess the socio-economic determinants of TB in HIV-infected patients in Asia. DESIGN: This was a matched case-control study. HIVpositive, TB-positive cases were matched to HIVpositive, TB-negative controls according to age, sex and CD4 cell count. A socio-economic questionnaire comprising 23 questions, including education level, employment, housing and substance use, was distributed. Socio-economic risk factors for TB were analysed using conditional logistic regression analysis. RESULT S : A total of 340 patients (170 matched pairs) were recruited, with 262 (77.1%) matched for all three criteria. Pulmonary TB was the predominant type (n = 115, 67.6%). The main risk factor for TB was not having a university level education (OR 4.45, 95%CI 1.50-13.17, P=0.007). Burning wood or coal regularly inside the house and living in the same place of origin were weakly associated with TB diagnosis. CONCLUS IONS : These data suggest that lower socioeconomic status is associated with an increased risk of TB in Asia. Integrating clinical and socio-economic factors into HIV treatment may help in the prevention of opportunistic infections and disease progression.