Publication:
Intestinal parasite infections in symptomatic children attending hospital in Siem Reap, Cambodia

dc.contributor.authorCatrin E. Mooreen_US
dc.contributor.authorPhot Ngeten_US
dc.contributor.authorMao Saroeunen_US
dc.contributor.authorSuy Kuongen_US
dc.contributor.authorSeng Chanthouen_US
dc.contributor.authorVarun Kumaren_US
dc.contributor.authorRachel Bousfielden_US
dc.contributor.authorJohanna Naderen_US
dc.contributor.authorJ. Wendi Baileyen_US
dc.contributor.authorNicholas J. Beechingen_US
dc.contributor.authorNicholas P. Dayen_US
dc.contributor.authorChristopher M. Parryen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherUniversity of Oxforden_US
dc.contributor.otherAngkor Hospital for Childrenen_US
dc.contributor.otherAddenbrooke's Hospitalen_US
dc.contributor.otherLiverpool School of Tropical Medicineen_US
dc.date.accessioned2018-11-23T09:31:01Z
dc.date.available2018-11-23T09:31:01Z
dc.date.issued2015-05-07en_US
dc.description.abstract© 2015 Moore et al. Background: Infections with helminths and other intestinal parasites are an important but neglected problem in children in developing countries. Accurate surveys of intestinal parasites in children inform empirical treatment regimens and can assess the impact of school based drug treatment programmes. There is limited information on this topic in Cambodia. Methods: In a prospective study of intestinal parasites in symptomatic children attending Angkor Hospital for Children, Siem Reap, Cambodia, April-June 2012, samples were examined by microscopy of a direct and concentrated fecal sample. Two culture methods for hookworm and Strongyloides stercoralis were employed when sufficient sample was received. Demographic, clinical and epidemiological data were collected. Principal Findings: We studied 970 samples from 865 children. The median (inter-quartile range) age of the children was 5.4 (1.9-9.2) years, 54% were male. The proportion of children with abdominal pain was 66.8%, diarrhea 34.9%, anemia 12.7% and malnutrition 7.4%. 458 parasitic infections were detected in 340 (39.3%) children. The most common parasites using all methods of detection were hookworm (14.3%), Strongyloides stercoralis (11.6%) and Giardia lamblia (11.2%). Giardia lamblia was most common in children aged 1-5 years, hookworm and Strongyloides stercoralis were more common with increasing age. Hookworm, Strongloides stercoralis and Giardia lamblia were more common in children living outside of Siem Reap town. In a multivariate logistic regression increasing age was associated with all three infections, defecating in the forest for hookworm infection, the presence of cattle for S. stercoralis and not using soap for handwashing for G. lamblia. Conclusions/Significance: This study confirms the importance of intestinal parasitic infections in symptomatic Cambodian children and the need for adequate facilities for laboratory diagnosis together with education to improve personal hygiene and sanitation.en_US
dc.identifier.citationPLoS ONE. Vol.10, No.5 (2015)en_US
dc.identifier.doi10.1371/journal.pone.0123719en_US
dc.identifier.issn19326203en_US
dc.identifier.other2-s2.0-84929094096en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/35164
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84929094096&origin=inwarden_US
dc.subjectAgricultural and Biological Sciencesen_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.titleIntestinal parasite infections in symptomatic children attending hospital in Siem Reap, Cambodiaen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84929094096&origin=inwarden_US

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