Publication: A mechanism of raft formation on both plasma membrane layers
Issued Date
2013-10-01
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ISSN
12860050
12860042
12860042
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2-s2.0-84885821938
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Mahidol University
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SCOPUS
Bibliographic Citation
EPJ Applied Physics. Vol.64, No.1 (2013)
Suggested Citation
Kan Sornbundit, Charin Modchang, Wannapong Triampo, Darapond Triampo, Narin Nuttavut A mechanism of raft formation on both plasma membrane layers. EPJ Applied Physics. Vol.64, No.1 (2013). doi:10.1051/epjap/2013130210 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/31994
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Title
A mechanism of raft formation on both plasma membrane layers
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Abstract
A double-layered membrane model is proposed to explain raft formation and induction on extracellular (outer) and cytoplasmic (inner) leaflets of plasma membranes in a situation where only the outer layer has a tendency to phase-separate. In the model, lipid exchange with the surrounding medium is allowed on both layers, but lipid exchange between layers is not allowed. Simulations display domain stabilization on both layers. The effect of the lipid recycling frequencies on stationary domain sizes is also investigated. It is found that stationary domain sizes decrease when lipid recycling frequencies are stronger. Linear stability analysis is used to verify the results. © 2013 EDP Sciences.