Publication: Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations
Issued Date
2006-02-01
Resource Type
ISSN
00359203
Other identifier(s)
2-s2.0-29744436385
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.100, No.2 (2006), 184-186
Suggested Citation
Paul N. Newton, Steven Ward, Brian J. Angus, Wirongrong Chierakul, Arjen Dondorp, Ronnatrai Ruangveerayuth, Kamolrat Silamut, Pramote Teerapong, Yupin Suputtamongkol, Sornchai Looareesuwan, Nicholas J. White Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations. Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.100, No.2 (2006), 184-186. doi:10.1016/j.trstmh.2005.01.008 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/23368
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Early treatment failure in severe malaria resulting from abnormally low plasma quinine concentrations
Abstract
A patient admitted with severe Plasmodium falciparum malaria in western Thailand had an early treatment failure with quinine, despite full dosing. Plasma quinine concentrations were subtherapeutic. Abnormal quinine pharmacokinetics may explain sporadic reports of quinine treatment failures in severe malaria. © 2005 Royal Society of Tropical Medicine Hygiene. Published by Elsevier Ltd. All rights reserved.