Publication: Paraquat exposure of pregnant women and neonates in agricultural areas in Thailand
Issued Date
2018-06-03
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ISSN
16604601
16617827
16617827
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2-s2.0-85048048709
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Mahidol University
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SCOPUS
Bibliographic Citation
International Journal of Environmental Research and Public Health. Vol.15, No.6 (2018)
Suggested Citation
Pajaree Konthonbut, Pornpimol Kongtip, Noppanun Nankongnab, Mathuros Tipayamongkholgul, Witaya Yoosook, Susan Woskie Paraquat exposure of pregnant women and neonates in agricultural areas in Thailand. International Journal of Environmental Research and Public Health. Vol.15, No.6 (2018). doi:10.3390/ijerph15061163 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/45880
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Title
Paraquat exposure of pregnant women and neonates in agricultural areas in Thailand
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Abstract
© 2018 by the authors. Licensee MDPI, Basel, Switzerland. This study aimed to assess paraquat concentrations in the urine of women at 28 weeks of pregnancy, delivery and 2 months postpartum and in the meconium of neonates. In all, 79 pregnant women were recruited from three hospitals located in agricultural areas in Thailand. The subjects were interviewed about personal characteristics, agricultural activities and pesticide use patterns. Paraquat was analyzed in urine and meconium using high performance liquid chromatography equipped with a fluorescence detector. The geometric mean (GSD) of urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum were 2.04 (4.22), 2.06 (5.04) and 2.42 (5.33) ng/mL, respectively. The urinary paraquat concentrations at 28 weeks of pregnancy, delivery and 2 months postpartum between agriculturist and non-agriculturist were not significantly different (p = 0.632, p = 0.915, p = 0.57 respectively). The geometric mean (GSD) of paraquat concentration in the meconium was 33.31 (4.59) ng/g. The factors predicting paraquat exposures among pregnant women and neonates included working outside, living near farmland, having family members who work on a farm, drinking well water and using herbicides or paraquat.