Publication:
The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs

Issued Date

1979-01-01

Resource Type

Article

ISSN

03784274

DOI

10.1016/0378-4274(79)90051-1

Other identifier(s)

2-s2.0-0018690628

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Toxicology Letters. Vol.4, No.5 (1979), 393-397

Suggested Citation

Yongyot Monsereenusorn, Thirayudth Glinsukon The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs. Toxicology Letters. Vol.4, No.5 (1979), 393-397. doi:10.1016/0378-4274(79)90051-1 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/13286

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Title

The inhibitory effect of capsaicin on intestinal glucose absorption in vitro. I. Effect of capsaicin on the serosal side of everted intestinal sacs

Author(s)

Yongyot Monsereenusorn
 Thirayudth Glinsukon

Other Contributor(s)

Mahidol University

Abstract

When 14.0 mg/100 ml capsaicin was placed onto the serosal solution for 30 and 60 min, intestinal glucose transport was inhibited by 30.24 and 56.62% in the rat, and 25.87 and 40.83% in the hamster, respectively. A significantly smaller amount of capsaicin was absorbed into the gut wall, and none appeared in the mucosal solution. It is suggested that capsaicin may inhibit the ATPasedependent sodium pump of the basolateral membrane, with consequent inhibition of intestinal glucose absorption. © 1979.

Keyword(s)

Pharmacology, Toxicology and Pharmaceutics

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/13286

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Scopus 1969-1990