Publication: Combined hepatocellular and cholangiocarcinoma: CT Findings with emphasis on multiphasic helical CT
Issued Date
2007-01-01
Resource Type
ISSN
01252208
01252208
01252208
Other identifier(s)
2-s2.0-33846977704
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Journal of the Medical Association of Thailand. Vol.90, No.1 (2007), 113-120
Suggested Citation
Sith Phongkitkarun, Tanop Srisuwan, Pattana Sornmayura, Janjira Jatchavala Combined hepatocellular and cholangiocarcinoma: CT Findings with emphasis on multiphasic helical CT. Journal of the Medical Association of Thailand. Vol.90, No.1 (2007), 113-120. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/25051
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Combined hepatocellular and cholangiocarcinoma: CT Findings with emphasis on multiphasic helical CT
Other Contributor(s)
Abstract
Objective: To describe CT findings of patients with combined hepatocellular carcinoma and cholangiocarcinoma (HCC-CC) in correlation with clinical data and histopathological results. Material and Method: Ten from 31 cases whose CT study was available were reviewed retrospectively in the aspect of imaging findings, clinical data, and pathological results. Results: Most of the tumors were hypodense solitary mass with gradually enhanced after contrast administration. Bile duct dilatation was observed in two cases. The overall CT findings were more similar to CC rather than HCC despite the pathological result showing predominant HCC component. Serum alpha-fetoprotein level was normal or mildly elevated while an elevated concentration of carbohydrate antigen 19-9 was observed. Hepatitis profiles showed positive to hepatitis B virus infection in four cases and hepatitis C virus infection in one case. Conclusion: The diagnosis of combined HCC-CC should be considered if the tumor has similar findings to CC without bile duct dilatation on cirrhotic liver and the patient has normal or low rising of the AFP level with or without elevated CA 19-9 level. In non-cirrhotic liver, the finding is non-specific.