Publication: Revisiting the Mechanisms of Immune Evasion Employed by Human Parasites
Issued Date
2021-07-29
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ISSN
22352988
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2-s2.0-85112420730
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Mahidol University
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SCOPUS
Bibliographic Citation
Frontiers in Cellular and Infection Microbiology. Vol.11, (2021)
Suggested Citation
Monrat Chulanetra, Wanpen Chaicumpa Revisiting the Mechanisms of Immune Evasion Employed by Human Parasites. Frontiers in Cellular and Infection Microbiology. Vol.11, (2021). doi:10.3389/fcimb.2021.702125 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/77258
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Title
Revisiting the Mechanisms of Immune Evasion Employed by Human Parasites
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Abstract
For the establishment of a successful infection, i.e., long-term parasitism and a complete life cycle, parasites use various diverse mechanisms and factors, which they may be inherently bestowed with, or may acquire from the natural vector biting the host at the infection prelude, or may take over from the infecting host, to outmaneuver, evade, overcome, and/or suppress the host immunity, both innately and adaptively. This narrative review summarizes the up-to-date strategies exploited by a number of representative human parasites (protozoa and helminths) to counteract the target host immune defense. The revisited information should be useful for designing diagnostics and therapeutics as well as vaccines against the respective parasitic infections.