Publication: Chikungunya virus was isolated in Thailand, 2010
Issued Date
2014-01-01
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ISSN
1572994X
09208569
09208569
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2-s2.0-84911375254
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Mahidol University
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SCOPUS
Bibliographic Citation
Virus Genes. Vol.49, No.3 (2014), 485-489
Suggested Citation
Mikiko Sasayama, Surachet Benjathummarak, Norihito Kawashita, Prasert Rukmanee, Suntaree Sangmukdanun, Promsin Masrinoul, Pannamthip Pitaksajjakul, Orapim Puiprom, Pitak Wuthisen, Takeshi Kurosu, Panjaporn Chaichana, Pannamas Maneekan, Kazuyoshi Ikuta, Pongrama Ramasoota, Tamaki Okabayashi, Pratap Singhasivanon, Natthanej Luplertlop Chikungunya virus was isolated in Thailand, 2010. Virus Genes. Vol.49, No.3 (2014), 485-489. doi:10.1007/s11262-014-1105-5 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/33453
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Title
Chikungunya virus was isolated in Thailand, 2010
Author(s)
Mikiko Sasayama
Surachet Benjathummarak
Norihito Kawashita
Prasert Rukmanee
Suntaree Sangmukdanun
Promsin Masrinoul
Pannamthip Pitaksajjakul
Orapim Puiprom
Pitak Wuthisen
Takeshi Kurosu
Panjaporn Chaichana
Pannamas Maneekan
Kazuyoshi Ikuta
Pongrama Ramasoota
Tamaki Okabayashi
Pratap Singhasivanon
Natthanej Luplertlop
Surachet Benjathummarak
Norihito Kawashita
Prasert Rukmanee
Suntaree Sangmukdanun
Promsin Masrinoul
Pannamthip Pitaksajjakul
Orapim Puiprom
Pitak Wuthisen
Takeshi Kurosu
Panjaporn Chaichana
Pannamas Maneekan
Kazuyoshi Ikuta
Pongrama Ramasoota
Tamaki Okabayashi
Pratap Singhasivanon
Natthanej Luplertlop
Other Contributor(s)
Abstract
© 2014, The Author(s). Chikungunya fever (CHIKF) is an acute febrile illness caused by a mosquito-borne alphavirus, chikungunya virus (CHIKV). This disease re-emerged in Kenya in 2004, and spread to the countries in and around the Indian Ocean. The re-emerging epidemics rapidly spread to regions like India and Southeast Asia, and it was subsequently identified in Europe in 2007, probably as a result of importation of chikungunya cases. On the one hand, chikungunya is one of the neglected diseases and has only attracted strong attention during large outbreaks. In 2008–2009, there was a major outbreak of chikungunya fever in Thailand, resulting in the highest number of infections in any country in the region. However, no update of CHIKV circulating in Thailand has been published since 2009. In this study, we examined the viral growth kinetics and sequences of the structural genes derived from CHIKV clinical isolates obtained from the serum specimens of CHIKF-suspected patients in Central Thailand in 2010. We identified the CHIKV harboring two mutations E1-A226V and E2-I211T, indicating that the East, Central, and South African lineage of CHIKV was continuously circulating as an indigenous population in Thailand.