Publication: Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy
Issued Date
2020-02-01
Resource Type
ISSN
14219735
02535068
02535068
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2-s2.0-85076800004
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Mahidol University
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SCOPUS
Bibliographic Citation
Blood Purification. Vol.49, No.1-2 (2020), 93-101
Suggested Citation
Thummaporn Naorungroj, Ary Serpa Neto, Lara Zwakman-Hessels, Fumitaka Yanase, Glenn Eastwood, Rinaldo Bellomo Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy. Blood Purification. Vol.49, No.1-2 (2020), 93-101. doi:10.1159/000503771 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/53769
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Title
Hourly Fluid Balance in Patients Receiving Continuous Renal Replacement Therapy
Abstract
© 2019 S. Karger AG, Basel. Little is known about early (first 48 h) hourly and cumulative fluid balance (FB) during continuous renal replacement therapy (CRRT). To study the characteristics and outcome associations of early hourly and cumulative FB. Methods: We studied FB in CRRT patients (2016-2018). Results: Among 350 patients, mean hourly FB became negative after 20 CRRT hours, but within 6 CRRT hours in patients with baseline fluid overload. A negative early FB was never achieved in patients receiving vasopressor therapy (p < 0.001). Mortality was 31%. The percentage of hourly negative FB was independently associated with decreased ICU mortality. A time-weighted hourly FB between 18.5 and -33 mL/h was also significantly and independently associated with decreased mortality. Conclusions: In CRRT patients, an early FB conservative approach is possible, modulated by patient characteristics, and associated with a low mortality. Moreover, avoidance of an early positive FB is associated with decreased mortality.