Publication: Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars
Issued Date
2007-02-01
Resource Type
ISSN
15244725
10760512
10760512
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2-s2.0-33846809479
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Mahidol University
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SCOPUS
Bibliographic Citation
Dermatologic Surgery. Vol.33, No.2 (2007), 152-161
Suggested Citation
Woraphong Manuskiatti, Rungsima Wanitphakdeedecha, Richard E. Fitzpatrick Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars. Dermatologic Surgery. Vol.33, No.2 (2007), 152-161. doi:10.1111/j.1524-4725.2006.33033.x Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25001
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Title
Effect of pulse width of a 595-nm flashlamp-pumped pulsed dye laser on the treatment response of keloidal and hypertrophic sternotomy scars
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Abstract
BACKGROUND: Flashlamp-pumped pulsed dye lasers (PDLs) have successfully treated keloidal and hypertrophic scars. OBJECTIVE: The objective was to investigate the effect of pulse width of a PDL in treating keloidal and hypertrophic scars. METHODS: On each of 19 patients, keloidal or hypertrophic median sternotomy scars were divided into two segments. Both segments on all patients were randomly treated with a 595-nm PDL at a fluence of 7 J/cm 2 and pulse widths of 0.45 and 40 ms to both segments, every 4 weeks for a total of three treatments. Scar volume, height, erythema, and pliability were measured at Weeks 0, 4, 8, and 24. RESULTS: The volume of segments treated with 0.45- and 40-ms pulses decreased significantly after two treatments. Segments treated with a 0.45-ms pulse width showed significantly greater improvement than those treated with 40-ms pulses after three treatments. Elasticity of 0.45-ms segments was significantly higher than those of 40-ms segments, following two treatments. Pulse width had no significant effect in improvement of scar erythema. CONCLUSIONS: A pulse width of 0.45 ms of PDL was more effective in decreasing scar size and improving scar pliability than that of 40 ms. A 595-nm PDL was safe and effective in treatment of hypertrophic scars and keloids in dark-skinned individuals. © 2007 by the American Society for Dermatologic Surgery, Inc.