Publication:
Genetic variation of nadh dehydrogenase subunit 1 (NAD1) mitochondrial gene sequence in adult necator Americanus hookworms recovered from a female patient in Thailand

Issued Date

2020-01-01

Resource Type

Article

ISSN

25219855
01275720

Other identifier(s)

2-s2.0-85087350280

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Tropical Biomedicine. Vol.37, No.2 (2020), 536-541

Suggested Citation

P. Eamsobhana, H. S. Yong, K. Roongruangchai, A. Tungtrongchitr, D. Wanachiwanawin Genetic variation of nadh dehydrogenase subunit 1 (NAD1) mitochondrial gene sequence in adult necator Americanus hookworms recovered from a female patient in Thailand. Tropical Biomedicine. Vol.37, No.2 (2020), 536-541. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/57981

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Title

Genetic variation of nadh dehydrogenase subunit 1 (NAD1) mitochondrial gene sequence in adult necator Americanus hookworms recovered from a female patient in Thailand

Author(s)

P. Eamsobhana
 H. S. Yong
 K. Roongruangchai
 A. Tungtrongchitr
 D. Wanachiwanawin

Other Contributor(s)

University of Malaya
 Faculty of Medicine, Siriraj Hospital, Mahidol University

Abstract

© 2020, Malaysian Society for Parasitology. All rights reserved. Two female and one male adult hookworms were recovered from a female patient in Thailand. Based on gross and microscopic morphology, the three hookworms are members of Necator americanus. Phylogenetic reconstruction based on partial NADH dehydrogenase subunit 1 (nad1) mitochondrial gene sequences shows that these hookworms belong to the same genetic lineage as N. americanus adult worm from Zhejiang, China. The male and female hookworms were genetically distinct, belonging to two different nad1-haplotypes. This is the first report targeting the nad1 gene on the identification and genetic characterization of the human hookworms originated from infected patient. The nad1 gene marker is useful for species and higher taxa differentiation of hookworms.

Keyword(s)

Immunology and Microbiology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/57981

Collections

Scopus 2020