Publication: Use of Xylazine in Drug-Facilitated Crimes
Issued Date
2018-07-01
Resource Type
ISSN
15564029
00221198
00221198
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2-s2.0-85032955356
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Forensic Sciences. Vol.63, No.4 (2018), 1325-1330
Suggested Citation
Jatupon Krongvorakul, Saranya Auparakkitanon, Satariya Trakulsrichai, Pitsucha Sanguanwit, Jetjamnong Sueajai, Nantida Noumjad, Winai Wananukul Use of Xylazine in Drug-Facilitated Crimes. Journal of Forensic Sciences. Vol.63, No.4 (2018), 1325-1330. doi:10.1111/1556-4029.13684 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/45109
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Use of Xylazine in Drug-Facilitated Crimes
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Abstract
© 2017 American Academy of Forensic Sciences Human xylazine poisoning is uncommon. This report describes the use of xylazine for intentional poisoning with criminal intent. Two incidents occurred within 3 weeks: the first involved one victim, and the second involved two victims. The clinical presentations were brief coma, bradycardia, hypotension, and hyperglycemia. The victims recalled having been given a drink from a stranger in a hospital waiting room before loss of consciousness. In the first case, general drug screening by gas chromatography/mass spectrometry (MS) revealed xylazine in the gastric contents, but liquid chromatography–tandem MS (LC-MS/MS) of serum did not. In the second incident, LC-MS/MS screening of both victims’ urine and serum samples revealed an unknown peak in the total ion chromatograms, which a molecular mass database identified as morantel or xylazine. The latter was confirmed by comparison with a xylazine standard. Based on this report, we suggest that xylazine should be classified as a controlled drug.
