Publication: Facile alcoholysis of l-lactide catalysed by Group 1 and 2 metal complexes
Issued Date
2008-06-10
Resource Type
ISSN
14779234
14779226
14779226
DOI
Other identifier(s)
2-s2.0-44649086363
Rights
Mahidol University
Rights Holder(s)
SCOPUS
Bibliographic Citation
Dalton Transactions. No.23 (2008), 3048-3050
Suggested Citation
Khamphee Phomphrai, Supathana Pracha, Phenphak Phonjanthuek, Manat Pohmakotr Facile alcoholysis of l-lactide catalysed by Group 1 and 2 metal complexes. Dalton Transactions. No.23 (2008), 3048-3050. doi:10.1039/b800308d Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/19079
Research Projects
Organizational Units
Authors
Journal Issue
Thesis
Title
Facile alcoholysis of l-lactide catalysed by Group 1 and 2 metal complexes
Other Contributor(s)
Abstract
The application of simple metal amides MN(SiMe3)2as effective catalysts for the alcoholysis of cyclic esters are demonstrated. Excess dry methanol and L-lactide were added to a Schlenk flask at room temperature (RT) 1 mol% of MN(SiMe3)2, where M = Li, Na or K was added. A blank test was also performed where no catalyst was added giving no reaction. The conversion of M = Li, 45% to methyl (S,S)-lactyllactatewas obtained in 10 minutes at room temperature. Similar behaviors were observed for m = Na and K, where the reactions decelerated after 20 and 30 minutes. The application also extended to other cyclic esters such as capralactone where the ring-opening product was obtained rapidly in quantitative yield.