Publication:
Preformation Versus Epigenesis in Early Mammalian Development

Issued Date

2016-12-01

Resource Type

Chapter

ISSN

00702153

DOI

10.1016/bs.ctdb.2015.11.006

Other identifier(s)

2-s2.0-84955574680

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Current Topics in Developmental Biology. Vol.117, (2016), 377-391

Suggested Citation

Davor Solter Preformation Versus Epigenesis in Early Mammalian Development. Current Topics in Developmental Biology. Vol.117, (2016), 377-391. doi:10.1016/bs.ctdb.2015.11.006 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/42692

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Title

Preformation Versus Epigenesis in Early Mammalian Development

Author(s)

Davor Solter

Other Contributor(s)

Mahidol University
 Max Planck Institute of Immunobiology and Epigenetics

Abstract

© 2016 Elsevier Inc. Whether or not early mammalian development results from preformation or epigenesis remains an unresolved issue. Evidence for or against either is weak, inconclusive, and often misinterpreted. Yet, one can parsimoniously conceptualize formation of the mouse blastocyst as a series of random, stochastic events stemming from initial and sequential small asymmetries in egg, zygote, and cleavage stages. Differential compartmentalized gene expression does not lead but follows the morphogenesis and cell fate allocation in the mammalian blastocyst.

Keyword(s)

Biochemistry, Genetics and Molecular Biology

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/42692

Collections

Scopus 2016-2017