Publication:
Revision primary total hip replacement: Causes and risk factors

dc.contributor.authorKhanin Iamthanapornen_US
dc.contributor.authorKeerati Chareancholvanichen_US
dc.contributor.authorChaturong Pornrattanamaneewongen_US
dc.contributor.otherPrince of Songkla Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-11-23T11:05:07Z
dc.date.available2018-11-23T11:05:07Z
dc.date.issued2015-01-01en_US
dc.description.abstract© 2015, Medical Association of Thailand. All rights reserved. Objective: To determine 1) causes of failure of primary total hip replacement (THR) in Thai patients and 2) whether patient characteristics, underlying diagnosis, and type of primary THR were associated with the causes of revision THR. Material and Method: The authors retrospectively reviewed all revision THRs in one referral hospital in Thailand between 2002 and 2012. All medical records and radiographic studies were used to identify the causes of primary THR failure. Randomly selected primary THRs performed in the same period were used to compare with revision THRs to determine the risk factors for revision. Results: This study included 219 THRs. After 5 years (late failure) from index surgery, 138 primary THRs (63.0%) were revised. Late failures were aseptic loosening (75.4%) followed by periprosthetic fracture (8.0%), and polyethylene wear (5.8%). The major reasons for revision surgery within 5 years (early failure) were periprosthetic joint infection (29.6%), aseptic loosening (28.4%), and instability (22.2%). Age <45 at index surgery had the lowest risk for revision with a hazards ratio of 0.695 (95% CI 0.492-0.981). Hybrid fixation was found to be a risk factor for revision THR with a hazards ratio of 1.652 (95% CI 1.166-2.341). Conclusion: Most THRs failed after 5 years. Periprosthetic joint infection was the most common cause of failure in the early period. Aseptic loosening was a major cause of failure in the late period and overall in both periods. Hybrid fixation is an independent risk factor for revision surgery after primary THR. Younger patients at the time of primary THR were associated with a reduced risk for failure.en_US
dc.identifier.citationJournal of the Medical Association of Thailand. Vol.98, No.1 (2015), 93-99en_US
dc.identifier.issn01252208en_US
dc.identifier.issn01252208en_US
dc.identifier.other2-s2.0-84924308359en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/36811
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84924308359&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleRevision primary total hip replacement: Causes and risk factorsen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84924308359&origin=inwarden_US

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