Publication: Antibody against a ring-infected erythrocyte surface antigen in cerebral and non-cerebral malaria patients
Issued Date
1988-01-01
Resource Type
ISSN
18783503
00359203
00359203
Other identifier(s)
2-s2.0-0023899737
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Mahidol University
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SCOPUS
Bibliographic Citation
Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.82, No.3 (1988), 385-388
Suggested Citation
Savanat Tharavanij, Pramuan Tapchaisri, Yuvadee Mahakunkijcharoen, Sornchai Looareesuwan Antibody against a ring-infected erythrocyte surface antigen in cerebral and non-cerebral malaria patients. Transactions of the Royal Society of Tropical Medicine and Hygiene. Vol.82, No.3 (1988), 385-388. doi:10.1016/0035-9203(88)90128-9 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15564
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Title
Antibody against a ring-infected erythrocyte surface antigen in cerebral and non-cerebral malaria patients
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Abstract
An indirect fluorescent antibody test for glutaral-dehyde-fixed, ring-infected erythrocyte surface anti-gen was performed on admission sera from 45 patients with complicated cerebral Plasmodium falciparum malaria, 33 with uncomplicated cerebral malaria, 91 non-cerebral malaria patients, and 53 blood donors from a non-malarious area. 14 (31%), 28 (85%), 64 (70%), and 1 (2%), respectively, had titres 3≥1/25, considered as positive. The seropositive rate and the geometric mean reciprocal titre of patients with complicated cerebral malaria were significantly lower than those of uncomplicated and non-cerebral patients, particularly in the 6-14 and 15-29 year age groups. Compared with non-cerebral patients, lower seropositive rates for patients with complicated cerebral malaria were demonstrated only in those who had been ill 4 or more days before admission; whereas lower rates for patients with complications, when compared with rates in those with uncomplicated cerebral malaria, occurred irrespective of the duration of illness. © 1988 Oxford University Press.