Publication:
The synthesis of wrightiadione via directed remote metalation

Issued Date

2003-01-01

Resource Type

Article

ISSN

09365214

DOI

10.1055/s-2003-39313

Other identifier(s)

2-s2.0-0038538272

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

Synlett. No.7 (2003), 1037-1039

Suggested Citation

Nopporm Thasana, Somsak Ruchirawat The synthesis of wrightiadione via directed remote metalation. Synlett. No.7 (2003), 1037-1039. doi:10.1055/s-2003-39313 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/20824

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Title

The synthesis of wrightiadione via directed remote metalation

Author(s)

Nopporm Thasana
 Somsak Ruchirawat

Other Contributor(s)

Chulabhorn Research Institute
 Mahidol University

Abstract

The application of directed remote metalation (DreM) and electrophilic substitution is reported for the synthesis of wrightiadione using N,N-diethylcarboxamide as a directed metalation group (DMG) and electrophilic group. The lithiation of N,N-diethylisoflavone-2′-carboxamide with LDA gave a carbanion at C-2 which further cyclized to wrightiadione.

Keyword(s)

Chemistry

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/20824

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Scopus 2001-2005