Publication: Determination of lidocaine in dental pulp by high-performance liquid chromatography
Issued Date
2001-01-01
Resource Type
ISSN
00992399
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2-s2.0-0035230556
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Mahidol University
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SCOPUS
Bibliographic Citation
Journal of Endodontics. Vol.27, No.1 (2001), 31-35
Suggested Citation
Somchart Kanjanawattana, Chutima Mangkornkarn, Prapin Wilairat, Noppakun Vongsavan Determination of lidocaine in dental pulp by high-performance liquid chromatography. Journal of Endodontics. Vol.27, No.1 (2001), 31-35. doi:10.1097/00004770-200101000-00009 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/26530
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Title
Determination of lidocaine in dental pulp by high-performance liquid chromatography
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Abstract
The purpose of this study was to develop a method for lidocaine detection in dental pulp by high-performance liquid chromatography. The amounts of lidocaine in dog pulps were quantitated after local injection to evaluate lidocaine recovery from pulp tissue with this technique. Comparison was also made between the amount of lidocaine found in upper and lower canines. The high-performance liquid chromatography system was shown to be a reliable and reproducible tool for lidocaine determination. Lidocaine extraction from the tissue showed recovery of 90%. The amount of lidocaine recovered from the upper canine (0.21 μg/mg) was higher than the lower canine (0.17 μg/mg). Copyright © 2001 by The American Association of Endodontists.