Publication:
Intracerebral hemorrhage following intravenous thrombolysis in Thai patients with acute ischemic stroke

dc.contributor.authorPornpatr A. Dharmasarojaen_US
dc.contributor.authorSombat Muengtaweepongsaen_US
dc.contributor.authorJunya Pattaraarchachaien_US
dc.contributor.authorPermphan Dharmasarojaen_US
dc.contributor.otherFaculty of Medicine, Thammasat Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-06-11T05:10:24Z
dc.date.available2018-06-11T05:10:24Z
dc.date.issued2012-06-01en_US
dc.description.abstractIn Asia, there is limited information regarding symptomatic intracerebral hemorrhage (ICH) in patients treated with intravenous (iv) recombinant tissue plasminogen activator (rtPA). The aim of this study was to identify independent factors associated with symptomatic ICH following iv rtPA. The study included 192 patients with acute ischemic stroke who were treated with iv rtPA. Baseline characteristics were compared between patients with or without ICH. Symptomatic ICH occurred in 5.7% of patients and asymptomatic ICH in 13.0% of patients. An international normalized ratio (INR) ≥1.0 (odds ratio [OR] = 4.89, p = 0.036), atrial fibrillation (OR = 7.21, p = 0.009) and blood glucose concentration > 8.325 mmol/L (OR = 9.00, p = 0.004), were independent risk factors for symptomatic ICH. Atrial fibrillation (OR = 3.56, p = 0.012) and severe stroke (National Institutes of Health Stroke Scale ≥15; OR = 8.94, p < 0.001) were independent risk factors for asymptomatic ICH. The prevalence of symptomatic ICH following iv rtPA in Thai patients was comparable to previous studies. © 2012 Elsevier Ltd. All rights reserved.en_US
dc.identifier.citationJournal of Clinical Neuroscience. Vol.19, No.6 (2012), 799-803en_US
dc.identifier.doi10.1016/j.jocn.2011.08.035en_US
dc.identifier.issn15322653en_US
dc.identifier.issn09675868en_US
dc.identifier.other2-s2.0-84861185258en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/14790
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861185258&origin=inwarden_US
dc.subjectMedicineen_US
dc.subjectNeuroscienceen_US
dc.titleIntracerebral hemorrhage following intravenous thrombolysis in Thai patients with acute ischemic strokeen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=84861185258&origin=inwarden_US

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