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Antiplasmodial sesquiterpene alkaloids from the roots of maytenus mekongensis

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dc.contributor.authorThitima Lhinhatrakoolen_US
dc.contributor.authorSamran Prabpaien_US
dc.contributor.authorPalangpon Kongsaereeen_US
dc.contributor.authorSomyote Sutthivaiyakiten_US
dc.contributor.otherRamkhamhaeng Universityen_US
dc.contributor.otherMahidol Universityen_US
dc.date.accessioned2018-05-03T08:02:03Z
dc.date.available2018-05-03T08:02:03Z
dc.date.issued2011-06-24en_US
dc.description.abstractEight new sesquiterpene alkaloids (1 - 8) and four known sesquiterpene alkaloids (9 - 12) have been isolated from the roots of Maytenus mekongensis. Structures were determined using extensive spectroscopic methods. The relative configuration of 7-epi-mekongensine (2) was established by single-crystal X-ray crystallographic analysis. The alkaloids were evaluated for antiplasmodial activity against Plasmodium falciparum, K1 strain, and for cytotoxicity using a panel of cell lines. © 2011 The American Chemical Society and American Society of Pharmacognosy.en_US
dc.identifier.citationJournal of Natural Products. Vol.74, No.6 (2011), 1386-1391en_US
dc.identifier.doi10.1021/np200014ken_US
dc.identifier.issn15206025en_US
dc.identifier.issn01633864en_US
dc.identifier.other2-s2.0-79959726526en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/20.500.14594/11530
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79959726526&origin=inwarden_US
dc.subjectBiochemistry, Genetics and Molecular Biologyen_US
dc.subjectChemistryen_US
dc.subjectMedicineen_US
dc.subjectPharmacology, Toxicology and Pharmaceuticsen_US
dc.titleAntiplasmodial sesquiterpene alkaloids from the roots of maytenus mekongensisen_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=79959726526&origin=inwarden_US

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