Publication: Application of preserved human amniotic membrane for corneal surface reconstruction
Issued Date
2000-12-01
Resource Type
ISSN
13899333
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2-s2.0-0000824333
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Mahidol University
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SCOPUS
Bibliographic Citation
Cell and Tissue Banking. Vol.1, No.3 (2000), 213-222
Suggested Citation
Pinnita Prabhasawat, Panida Kosrirukvongs, Wipawee Booranapong, Yongyudh Vajaradul Application of preserved human amniotic membrane for corneal surface reconstruction. Cell and Tissue Banking. Vol.1, No.3 (2000), 213-222. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/25840
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Title
Application of preserved human amniotic membrane for corneal surface reconstruction
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Abstract
Objective: To evaluate the efficacy of preserved human amniotic membrane transplantation for reconstruction of the corneal surface diseases. Methods: Preserved human amniotic membrane transplantations were performed in 84 eyes of 78 patients for corneal surface reconstruction. The indications were limbal stem cell deficiency from Steven-Johnson syndrome, chemical burn and herpes keratitis (27 eyes), bullous keratopathy (26 eyes), persistent epithelial defect and dellen (17 eyes), band keratopathy (11 eyes), preparing for prosthesis (1 eye), corneal ulcer (1 eye) and acute chemical burn (1 eye). Results: Success was noted in 83.3% (70/84) eyes, partial success in 13.1% (11/84) eyes, and failure in 3.6% (3/84) eyes for an average follow-up of 10.5 months (3 - 29 months). No patient developed major immediate post-operative complications. Conclusion: Amniotic membrane transplantation can reduce inflammation, promote corneal epithelial healing, and decrease irritation in corneal surface problems. © 2000 Kluwer Academic Publishers.