Publication: Herpes simplex virus type-2, cytomegalovirus and Epstein-Barr virus infection in acute non A to E hepatitis Thai patients
Issued Date
1997-09-01
Resource Type
ISSN
0125877X
Other identifier(s)
2-s2.0-17344370155
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Mahidol University
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SCOPUS
Bibliographic Citation
Asian Pacific Journal of Allergy and Immunology. Vol.15, No.3 (1997), 147-151
Suggested Citation
Yaowapa Maneerat, Polrat Wilairatana, Emsri Pongponratn, Pilaipan Puthavathana, Urai Chaisri, Sucha Kurathong, Anuchit Juthaputhi, Edward T. Clayson, Rapin Snitbhan, Boonyos Raengsakulrach, David W. Vaughn Herpes simplex virus type-2, cytomegalovirus and Epstein-Barr virus infection in acute non A to E hepatitis Thai patients. Asian Pacific Journal of Allergy and Immunology. Vol.15, No.3 (1997), 147-151. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/18104
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Title
Herpes simplex virus type-2, cytomegalovirus and Epstein-Barr virus infection in acute non A to E hepatitis Thai patients
Abstract
A significant number of acute non A to E hepatitis cases are reported in Thailand every year, and the etiologies of these cases are unknown. Members of the herpesviridae family have been reported to cause either a self limited or fatal hepatitis in a small proportion of patients in other parts of the world. To determine whether herpesviruses may play a role in acute non A to E hepatitis, sera from 32 acute hepatitis patients without markers for acute hepatitis A to E virus infection were examined for IgM to herpesvirus type 2 (HSV-2), cytomegalovirus (CMV), and Epstein-Barr virus (EBV) using commercially available assays. IgM to HSV-2 was detected in four sera, IgM to CMV was detected in one serum, and IgM to EBV was detected in one serum. All of the acute non A to E hepatitis patients recovered and none had underlying conditions associated with impaired immunity. These results suggest that herpesviruses should be considered in the differential diagnosis for Thai patients with hepatitis.