Publication: Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host
Issued Date
2018-12-01
Resource Type
ISSN
20452322
Other identifier(s)
2-s2.0-85045404571
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Mahidol University
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SCOPUS
Bibliographic Citation
Scientific Reports. Vol.8, No.1 (2018)
Suggested Citation
Morakot Kaewthamasorn, Mika Takeda, Tawee Saiwichai, Jesse N. Gitaka, Sonthaya Tiawsirisup, Yuhei Imasato, Ehab Mossaad, Ali Sarani, Winai Kaewlamun, Manun Channumsin, Suchart Chaiworakul, Wichit Katepongpun, Surapong Teeveerapunya, Jarus Panthong, Dominic K. Mureithi, Saw Bawm, Lat Lat Htun, Mar Mar Win, Ahmed Ali Ismail, Abdalla Mohamed Ibrahim, Keisuke Suganuma, Hassan Hakimi, Ryo Nakao, Ken Katakura, Masahito Asada, Osamu Kaneko Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host. Scientific Reports. Vol.8, No.1 (2018). doi:10.1038/s41598-018-24048-0 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/47502
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Title
Genetic homogeneity of goat malaria parasites in Asia and Africa suggests their expansion with domestic goat host
Author(s)
Morakot Kaewthamasorn
Mika Takeda
Tawee Saiwichai
Jesse N. Gitaka
Sonthaya Tiawsirisup
Yuhei Imasato
Ehab Mossaad
Ali Sarani
Winai Kaewlamun
Manun Channumsin
Suchart Chaiworakul
Wichit Katepongpun
Surapong Teeveerapunya
Jarus Panthong
Dominic K. Mureithi
Saw Bawm
Lat Lat Htun
Mar Mar Win
Ahmed Ali Ismail
Abdalla Mohamed Ibrahim
Keisuke Suganuma
Hassan Hakimi
Ryo Nakao
Ken Katakura
Masahito Asada
Osamu Kaneko
Mika Takeda
Tawee Saiwichai
Jesse N. Gitaka
Sonthaya Tiawsirisup
Yuhei Imasato
Ehab Mossaad
Ali Sarani
Winai Kaewlamun
Manun Channumsin
Suchart Chaiworakul
Wichit Katepongpun
Surapong Teeveerapunya
Jarus Panthong
Dominic K. Mureithi
Saw Bawm
Lat Lat Htun
Mar Mar Win
Ahmed Ali Ismail
Abdalla Mohamed Ibrahim
Keisuke Suganuma
Hassan Hakimi
Ryo Nakao
Ken Katakura
Masahito Asada
Osamu Kaneko
Other Contributor(s)
Mount Kenya University
Rajamangala University of Technology system
University of Zabol
Sudan University of Science and Technology
Chulalongkorn University
Hokkaido University
Mahidol University
Nagasaki University
Obihiro University of Agriculture and Veterinary Medicine
Livestock Office of Phetchaburi Province
Livestock Office of Kaeng Krachan District
Abrar University Somalia
University of Veterinary Science
Rajamangala University of Technology system
University of Zabol
Sudan University of Science and Technology
Chulalongkorn University
Hokkaido University
Mahidol University
Nagasaki University
Obihiro University of Agriculture and Veterinary Medicine
Livestock Office of Phetchaburi Province
Livestock Office of Kaeng Krachan District
Abrar University Somalia
University of Veterinary Science
Abstract
© 2018 The Author(s). Plasmodium was first identified in a goat in Angola in 1923, and only recently characterized by DNA isolation from a goat blood sample in Zambia. Goats were first domesticated in the Fertile Crescent approximately 10,000 years ago, and are now globally distributed. It is not known if the Plasmodium identified in African goats originated from parasites circulating in the local ungulates, or if it co-evolved in the goat before its domestication. To address this question, we performed PCR-based surveillance using a total of 1,299 goat blood samples collected from Sudan and Kenya in Africa, Iran in west Asia, and Myanmar and Thailand in southeast Asia. Plasmodium DNA was detected from all locations, suggesting that the parasite is not limited to Africa, but widely distributed. Whole mitochondrial DNA sequences revealed that there was only one nucleotide substitution between Zambian/Kenyan samples and others, supporting the existence of a goat-specific Plasmodium species, presumably Plasmodium caprae, rather than infection of goats by local ungulate malaria parasites. We also present the first photographic images of P. caprae, from one Kenyan goat sample.