S. Indraprasit, C. O. Sooksriwongse Effect of chlorpromazine on peritoneal clearances. Nephron. Vol.40, No.3 (1985), 341-343. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/30760
Chlorpromazine added to the dialysate improved the ultrafiltration and increased peritoneal clearances of urea and inulin. These results were postulated to be due to narrowed stagnant dialysate fluid layer by the surface-active property of chlorpromazine. The study suggested another way to improve large solute (possibly uremic toxin) transport by using substances that facilitate convective transport. Intraperitoneal chlorpromazine increased the peritoneal dialysis efficiency.
