Publication: Repeated doses of albendazole against strongyloidiasis in Thai children.
Issued Date
1989-06-01
Resource Type
ISSN
01251562
Other identifier(s)
2-s2.0-0024677222
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Mahidol University
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SCOPUS
Bibliographic Citation
The Southeast Asian journal of tropical medicine and public health. Vol.20, No.2 (1989), 221-226
Suggested Citation
P. Chanthavanich, P. Nontasut, V. Prarinyanuparp, S. Sa-Nguankiat Repeated doses of albendazole against strongyloidiasis in Thai children.. The Southeast Asian journal of tropical medicine and public health. Vol.20, No.2 (1989), 221-226. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/15809
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Title
Repeated doses of albendazole against strongyloidiasis in Thai children.
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Abstract
Fifty children aged 5 to 12 years whose fecal examination confirmed of strongyloidiasis were divided into 2 groups. One group (Group I) of 26 received 400 mg albendazole once a day for 3 consecutive days. The other group (Group II) of 24 received the same dosage but repeated a week later. Simple smear fecal examination was performed for 3 consecutive days before treatment, and stool cultures were performed on Days 13, 14, 15 21, 22 and 23 after treatment. Evaluation of successful treatment or cure was based on the absence of larvae in 6 culture specimens. The cure rates were 80.8% in Group I and 91.7% in Group II (p = 0.18). Side effect consisted of mild and transient vomiting in one patient in each group. Although the difference in cure rates between the two drug regimens was not statistically different, two courses of treatment (Group II) resulted in a higher cure rate.