Publication: Factors affecting orthogonality in the deprotection of 2,4-di-protected aromatic ethers employing solid-supported acids
| dc.contributor.author | Kassrin Tangdenpaisal | en_US |
| dc.contributor.author | Supannee Sualek | en_US |
| dc.contributor.author | Somsak Ruchirawat | en_US |
| dc.contributor.author | Poonsakdi Ploypradith | en_US |
| dc.contributor.other | Chulabhorn Research Institute | en_US |
| dc.contributor.other | Center for Environmental Health | en_US |
| dc.contributor.other | The Institute of Science and Technology for Research and Development, Mahidol University | en_US |
| dc.date.accessioned | 2018-09-13T06:24:35Z | |
| dc.date.available | 2018-09-13T06:24:35Z | |
| dc.date.issued | 2009-05-30 | en_US |
| dc.description.abstract | Selective deprotection of aromatic ethers bearing two protecting groups on the same aromatic ring by solid-supported acids (Amberlyst-15 and PTS-Si) was systematically investigated. ortho-Directing protonation by the carbonyl group as well as carbocation stability and quenching are the important determining factors for the orthogonal deprotection process. Stablilized carbocations (e.g., those from the MOM and PMB groups) could be removed with high selectivity. © 2009 Elsevier Ltd. All rights reserved. | en_US |
| dc.identifier.citation | Tetrahedron. Vol.65, No.22 (2009), 4316-4325 | en_US |
| dc.identifier.doi | 10.1016/j.tet.2009.03.089 | en_US |
| dc.identifier.issn | 00404020 | en_US |
| dc.identifier.other | 2-s2.0-65349143683 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/27221 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=65349143683&origin=inward | en_US |
| dc.subject | Biochemistry, Genetics and Molecular Biology | en_US |
| dc.subject | Chemistry | en_US |
| dc.subject | Pharmacology, Toxicology and Pharmaceutics | en_US |
| dc.title | Factors affecting orthogonality in the deprotection of 2,4-di-protected aromatic ethers employing solid-supported acids | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=65349143683&origin=inward | en_US |