Publication: Plasmepsin II inhibitory activity of alkoxylated and hydroxylated chalcones
| dc.contributor.author | Nongluk Sriwilaijaroen | en_US |
| dc.contributor.author | Mei Liu | en_US |
| dc.contributor.author | Mei Lin Go | en_US |
| dc.contributor.author | Prapon Wilairat | en_US |
| dc.contributor.other | Mahidol University | en_US |
| dc.contributor.other | University of | en_US |
| dc.date.accessioned | 2018-08-20T07:15:04Z | |
| dc.date.available | 2018-08-20T07:15:04Z | |
| dc.date.issued | 2006-07-01 | en_US |
| dc.description.abstract | Sixteen antimalarial alkoxylated and hydroxylated chalcones were tested for their ability to inhibit recombinant plasmepsin II in vitro. The best inhibitory compounds had either a chloro or dimethylamino group at the 4-position of phenyl ring A in the chalcone template. Combination of the chalcones with chloroquine showed additivity or mild antagonism of Plasmodium falciparum K1 growth in culture. | en_US |
| dc.identifier.citation | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.37, No.4 (2006), 607-612 | en_US |
| dc.identifier.issn | 01251562 | en_US |
| dc.identifier.other | 2-s2.0-33750217087 | en_US |
| dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/123456789/23702 | |
| dc.rights | Mahidol University | en_US |
| dc.rights.holder | SCOPUS | en_US |
| dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750217087&origin=inward | en_US |
| dc.subject | Medicine | en_US |
| dc.title | Plasmepsin II inhibitory activity of alkoxylated and hydroxylated chalcones | en_US |
| dc.type | Article | en_US |
| dspace.entity.type | Publication | |
| mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=33750217087&origin=inward | en_US |
