Publication:
Immune responses of selected phagotopes from monoclonal antibodies of Burkholderia pseudomallei

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dc.contributor.authorNarisorn Na-ngamen_US
dc.contributor.authorThareerat Kalambahetien_US
dc.contributor.authorPattama Ekpoen_US
dc.contributor.authorAnnamthip Pitaksajjakulen_US
dc.contributor.authorNatsuda Jamornthanyawaten_US
dc.contributor.authorNarisara Chantratitaen_US
dc.contributor.authorStitaya Sirisinhaen_US
dc.contributor.authorVisanu Thamlikitkulen_US
dc.contributor.authorWanpen Chaicumpaen_US
dc.contributor.authorMontarop Yamabhaien_US
dc.contributor.authorPongrama Ramasootaen_US
dc.contributor.otherKhon Kaen Universityen_US
dc.contributor.otherDepartment of Microbiology and Immunologyen_US
dc.contributor.otherMahidol Universityen_US
dc.contributor.otherSuranaree University of Technologyen_US
dc.date.accessioned2018-07-12T02:43:39Z
dc.date.available2018-07-12T02:43:39Z
dc.date.issued2008-05-01en_US
dc.description.abstractRandom peptide libraries displayed by bacteriophage T7 and M13 were employed to identify mimotopes from 4 monoclonal antibodies (MAbs) specific to Burkholderia pseudomallei. Insert DNA sequences of bound phages selected from four rounds of panning with each MAb revealed peptide sequences corresponding to B. pseudomallei K96243 hypothetical protein BPSL2046, hypothetical protein BpseP_02000035, B. pseudomallei K96243 hypothetical protein BPSS0784, B. pseudomallei 1710b hypothetical protein BURPS1710b_1104, and 6. cenocepacia H12424 TonB-dependent siderophore receptor, all located at the outer membrane. The immune responses from all selected phagotopes were significantly higher than that of lipopolysaccharide. The study demonstrates the feasibility of identifying mimotopes through screening of phage-displayed random peptide libraries with B. pseudomallei MAbs.en_US
dc.identifier.citationSoutheast Asian Journal of Tropical Medicine and Public Health. Vol.39, No.3 (2008), 443-451en_US
dc.identifier.issn01251562en_US
dc.identifier.other2-s2.0-44949204551en_US
dc.identifier.urihttps://repository.li.mahidol.ac.th/handle/123456789/19693
dc.rightsMahidol Universityen_US
dc.rights.holderSCOPUSen_US
dc.source.urihttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=44949204551&origin=inwarden_US
dc.subjectMedicineen_US
dc.titleImmune responses of selected phagotopes from monoclonal antibodies of Burkholderia pseudomalleien_US
dc.typeArticleen_US
dspace.entity.typePublication
mu.datasource.scopushttps://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=44949204551&origin=inwarden_US

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