Publication: Treatment of giardiasis in children with tinidazole, ornidazole and metronidazole
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Issued Date
1981-01-01
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ISSN
00383619
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2-s2.0-0019864672
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Mahidol University
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SCOPUS
Bibliographic Citation
Southeast Asian Journal of Tropical Medicine and Public Health. Vol.12, No.2 (1981), 231-235
Suggested Citation
V. Suntornpoch, B. Chavalittamrong Treatment of giardiasis in children with tinidazole, ornidazole and metronidazole. Southeast Asian Journal of Tropical Medicine and Public Health. Vol.12, No.2 (1981), 231-235. Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/30240
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Title
Treatment of giardiasis in children with tinidazole, ornidazole and metronidazole
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Abstract
121 children under 12 years of age suffering from giardiasis documented by the presence of cysts or trophozoites of G. lamblia in the stools were treated with a single-dose of 50 mg/kg body weight of tinidazole or ornidazole or by metronidazole given at a dosage of 20 mg/kg/day for 5 days. There was no statistical difference in the cure rate of the three drug regimens, which were respectively 94%, 95% and 97%. Side-effects were observed in 6 out of 48 patients (12.5%) with tinidazole (vomiting), in 11 out of 40 patients (27.5%) with ornidazole (vomiting and in 4 cases dizziness and one case drowsiness) and in 2 out of 33 patients (6%) in metronidazole (vomiting). Since side-effects were acceptable and temporary we think that both tinidazole and ornidazole are more convenient to treat giardiasis because these drugs can be given in a single-dose.