Publication: Cloning and heterologous expression of Cryptococcus neoformans CnSRB1 cDNA in Saccharomyces cerevisiae
dc.contributor.author | Saradee Warit | en_US |
dc.contributor.author | Lubomira I. Stateva | en_US |
dc.contributor.author | Prasit Palittapongarnpim | en_US |
dc.contributor.other | Thailand National Center for Genetic Engineering and Biotechnology | en_US |
dc.contributor.other | University of Manchester | en_US |
dc.contributor.other | Mahidol University | en_US |
dc.date.accessioned | 2018-07-12T02:43:32Z | |
dc.date.available | 2018-07-12T02:43:32Z | |
dc.date.issued | 2008-05-01 | en_US |
dc.description.abstract | In this study, we report the results of cloning, sequencing and functional analysis by complementation test of the putative Cryptococcus neoformans homolog CnSRB1. The nucleotide sequence revealed 63% identity, and the deduced amino acid sequence showed 66 and 64% identity to its respective homolog of Saccharomyces cerevisiae and Candida albicans, respectively. Functional complementation test indicated that the putative CnSRB1 gene could compensate the defect caused by a mutation in ScSRB1 in the S. cerevisiae srb1 mutant. Taken together, these results suggest that the putative CnSrb1p is a functional homolog of ScSrb1p. | en_US |
dc.identifier.citation | Southeast Asian Journal of Tropical Medicine and Public Health. Vol.39, No.3 (2008), 484-491 | en_US |
dc.identifier.issn | 01251562 | en_US |
dc.identifier.other | 2-s2.0-44949174994 | en_US |
dc.identifier.uri | https://repository.li.mahidol.ac.th/handle/20.500.14594/19685 | |
dc.rights | Mahidol University | en_US |
dc.rights.holder | SCOPUS | en_US |
dc.source.uri | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=44949174994&origin=inward | en_US |
dc.subject | Medicine | en_US |
dc.title | Cloning and heterologous expression of Cryptococcus neoformans CnSRB1 cDNA in Saccharomyces cerevisiae | en_US |
dc.type | Article | en_US |
dspace.entity.type | Publication | |
mu.datasource.scopus | https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=44949174994&origin=inward | en_US |