Publication:
A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications

Issued Date

2018-05-01

Resource Type

Review

ISSN

14716771
00070912

DOI

10.1016/j.bja.2018.02.007

Other identifier(s)

2-s2.0-85045581772

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

British Journal of Anaesthesia. Vol.120, No.5 (2018), 1066-1079

Suggested Citation

T. E.F. Abbott, A. J. Fowler, P. Pelosi, M. Gama de Abreu, A. M. Møller, J. Canet, B. Creagh-Brown, M. Mythen, T. Gin, M. M. Lalu, E. Futier, M. P. Grocott, M. J. Schultz, R. M. Pearse, P. Myles, T. J. Gan, A. Kurz, P. Peyton, D. Sessler, M. Tramèr, A. Cyna, G. S. De Oliveira, C. Wu, M. Jensen, H. Kehlet, M. Botti, O. Boney, G. Haller, T. Cook, L. Fleisher, M. Neuman, D. Story, R. Gruen, S. Bampoe, Lis Evered, D. Scott, B. Silbert, D. van Dijk, C. Kalkman, M. Chan, H. Grocott, R. Eckenhoff, L. Rasmussen, L. Eriksson, S. Beattie, D. Wijeysundera, G. Landoni, K. Leslie, B. Biccard, S. Howell, P. Nagele, T. Richards, A. Lamy, M. Gabreu, A. Klein, T. Corcoran, D. Jamie Cooper, S. Dieleman, E. Diouf, D. McIlroy, R. Bellomo, A. Shaw, J. Prowle, K. Karkouti, J. Billings, D. Mazer, M. Jayarajah, M. Murphy, J. Bartoszko, R. Sneyd, S. Morris, R. George, R. Moonesinghe, M. Shulman, M. Lane-Fall, U. Nilsson, N. Stevenson, W. van Klei, L. Cabrini, T. Miller, N. Pace, S. Jackson, D. Buggy, T. Short, B. Riedel, V. Gottumukkala, B. Alkhaffaf, M. Johnson A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications. British Journal of Anaesthesia. Vol.120, No.5 (2018), 1066-1079. doi:10.1016/j.bja.2018.02.007 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/46744

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications

Author(s)

T. E.F. Abbott
 A. J. Fowler
 P. Pelosi
 M. Gama de Abreu
 A. M. Møller
 J. Canet
 B. Creagh-Brown
 M. Mythen
 T. Gin
 M. M. Lalu
 E. Futier
 M. P. Grocott
 M. J. Schultz
 R. M. Pearse
 P. Myles
 T. J. Gan
 A. Kurz
 P. Peyton
 D. Sessler
 M. Tramèr
 A. Cyna
 G. S. De Oliveira
 C. Wu
 M. Jensen
 H. Kehlet
 M. Botti
 O. Boney
 G. Haller
 T. Cook
 L. Fleisher
 M. Neuman
 D. Story
 R. Gruen
 S. Bampoe
 Lis Evered
 D. Scott
 B. Silbert
 D. van Dijk
 C. Kalkman
 M. Chan
 H. Grocott
 R. Eckenhoff
 L. Rasmussen
 L. Eriksson
 S. Beattie
 D. Wijeysundera
 G. Landoni
 K. Leslie
 B. Biccard
 S. Howell
 P. Nagele
 T. Richards
 A. Lamy
 M. Gabreu
 A. Klein
 T. Corcoran
 D. Jamie Cooper
 S. Dieleman
 E. Diouf
 D. McIlroy
 R. Bellomo
 A. Shaw
 J. Prowle
 K. Karkouti
 J. Billings
 D. Mazer
 M. Jayarajah
 M. Murphy
 J. Bartoszko
 R. Sneyd
 S. Morris
 R. George
 R. Moonesinghe
 M. Shulman
 M. Lane-Fall
 U. Nilsson
 N. Stevenson
 W. van Klei
 L. Cabrini
 T. Miller
 N. Pace
 S. Jackson
 D. Buggy
 T. Short
 B. Riedel
 V. Gottumukkala
 B. Alkhaffaf
 M. Johnson

Other Contributor(s)

Ospedale Policlinico San Martino
 Royal Surrey County Hospital
 Hospital Universitari Germans Trias i Pujol
 Dresden University Faculty of Medicine and University Hospital Carl Gustav Carus
 University of Southampton, Faculty of Medicine
 UCL
 Queen Mary, University of London
 University of Surrey
 Amtssygehuset i Herlev
 Mahidol University
 Centre Hospitalier Universitaire de Clermont-Ferrand
 Chinese University of Hong Kong
 Ottawa Hospital Research Institute
 Amsterdam UMC - University of Amsterdam
 University Hospital Southampton NHS Foundation Trust

Abstract

© 2018 British Journal of Anaesthesia Background: There is a need for robust, clearly defined, patient-relevant outcome measures for use in randomised trials in perioperative medicine. Our objective was to establish standard outcome measures for postoperative pulmonary complications research. Methods: A systematic literature search was conducted using MEDLINE, Web of Science, SciELO, and the Korean Journal Database. Definitions were extracted from included manuscripts. We then conducted a three-stage Delphi consensus process to select the optimal outcome measures in terms of methodological quality and overall suitability for perioperative trials. Results: From 2358 records, the full texts of 81 manuscripts were retrieved, of which 45 met the inclusion criteria. We identified three main categories of outcome measure specific to perioperative pulmonary outcomes: (i) composite outcome measures of multiple pulmonary outcomes (27 definitions); (ii) pneumonia (12 definitions); and (iii) respiratory failure (six definitions). These were rated by the group according to suitability for routine use. The majority of definitions were given a low score, and many were imprecise, difficult to apply consistently, or both, in large patient populations. A small number of highly rated definitions were identified as appropriate for widespread use. The group then recommended four outcome measures for future use, including one new definition. Conclusions: A large number of postoperative pulmonary outcome measures have been used, but most are poorly defined. Our four recommended outcome measures include a new definition of postoperative pulmonary complications, incorporating an assessment of severity. These definitions will meet the needs of most clinical effectiveness trials of treatments to improve postoperative pulmonary outcomes.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/46744

Collections

Scopus 2018