Publication:
Human plasmodium vivax diversity, population structure and evolutionary origin

1

Issued Date

2020-01-01

Resource Type

Article

ISSN

19352735
19352727

DOI

10.1371/journal.pntd.0008072

Other identifier(s)

2-s2.0-85082145367

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

PLoS Neglected Tropical Diseases. Vol.14, No.3 (2020), 1-17

Suggested Citation

Virginie Rougeron, Eric Elguero, Céline Arnathau, Beatriz Acuña Hidalgo, Patrick Durand, Sandrine Houze, Antoine Berry, Sedigheh Zakeri, Rashidul Haque, Mohammad Shafiul Alam, François Nosten, Carlo Severini, Tamirat Gebru Woldearegai, Benjamin Mordmüller, Peter Gottfried Kremsner, Lilia González-Cerón, Gustavo Fontecha, Dionicia Gamboa, Lise Musset, Eric Legrand, Oscar Noya, Tepanata Pumpaibool, Pingchai Harnyuttanakorn, Khadijetou Mint Lekweiry, Musab Mohamad Albsheer, Muzamil Mahdi Abdel Hamid, Ali Ould Mohamed Salem Boukary, Jean François Trape, François Renaud, Franck Prugnolle Human plasmodium vivax diversity, population structure and evolutionary origin. PLoS Neglected Tropical Diseases. Vol.14, No.3 (2020), 1-17. doi:10.1371/journal.pntd.0008072 Retrieved from: https://repository.li.mahidol.ac.th/handle/123456789/54693

Research Projects

Organizational Units

Authors

Journal Issue

Thesis

Title

Human plasmodium vivax diversity, population structure and evolutionary origin

Author(s)

Virginie Rougeron
 Eric Elguero
 Céline Arnathau
 Beatriz Acuña Hidalgo
 Patrick Durand
 Sandrine Houze
 Antoine Berry
 Sedigheh Zakeri
 Rashidul Haque
 Mohammad Shafiul Alam
 François Nosten
 Carlo Severini
 Tamirat Gebru Woldearegai
 Benjamin Mordmüller
 Peter Gottfried Kremsner
 Lilia González-Cerón
 Gustavo Fontecha
 Dionicia Gamboa
 Lise Musset
 Eric Legrand
 Oscar Noya
 Tepanata Pumpaibool
 Pingchai Harnyuttanakorn
 Khadijetou Mint Lekweiry
 Musab Mohamad Albsheer
 Muzamil Mahdi Abdel Hamid
 Ali Ould Mohamed Salem Boukary
 Jean François Trape
 François Renaud
 Franck Prugnolle

Other Contributor(s)

University of Nouakchott (Université de Nouakchott)
 Universidad Peruana Cayetano Heredia, Instituto de Medicina Tropical Alexander von Humboldt
 Maladies Infectieuses et Vecteurs : Écologie, Génétique, Évolution et Contrôle
 Aix Marseille Université
 Universidad Nacional Autónoma de Honduras
 Institut Pasteur de la Guyane
 Khartoum University
 Haramaya University
 Chulalongkorn University
 Universite Paul Sabatier Toulouse III
 CHU de Toulouse
 Hôpital Bichat-Claude-Bernard AP-HP
 Instituto Nacional de Salud Pública. México
 Universität Tübingen
 Mahidol University
 International Centre for Diarrhoeal Disease Research Bangladesh
 Istituto Superiore Di Sanita
 Pasteur Institute of Iran
 Institut Pasteur, Paris
 Universidad Central de Venezuela
 German Center for Infection Research (DZIF)
 Centre for Tropical Medicine

Abstract

© 2020 Rougeron et al. More than 200 million malaria clinical cases are reported each year due to Plasmodium vivax, the most widespread Plasmodium species in the world. This species has been neglected and understudied for a long time, due to its lower mortality in comparison with Plasmodium falciparum. A renewed interest has emerged in the past decade with the dis-covery of antimalarial drug resistance and of severe and even fatal human cases. Nonethe-less, today there are still significant gaps in our understanding of the population genetics and evolutionary history of P. vivax, particularly because of a lack of genetic data from Africa. To address these gaps, we genotyped 14 microsatellite loci in 834 samples obtained from 28 locations in 20 countries from around the world. We discuss the worldwide population genetic structure and diversity and the evolutionary origin of P. vivax in the world and its introduction into the Americas. This study demonstrates the importance of conducting genome-wide analyses of P. vivax in order to unravel its complex evolutionary history.

Keyword(s)

Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/123456789/54693

Collections

Scopus 2020