Publication:
Assessment of adult women with ovarian masses and treatment of epithelial ovarian cancer: Asco resource-stratified guideline

Issued Date

2021-01-01

Resource Type

Article

ISSN

26878941

DOI

10.1200/GO.21.00085

Other identifier(s)

2-s2.0-85110025454

Rights

Mahidol University

Rights Holder(s)

SCOPUS

Bibliographic Citation

JCO Global Oncology. Vol.7, (2021), 1032-1066

Suggested Citation

Verna D. Vanderpuye, Jean Rene V. Clemenceau, Sarah Temin, Zeba Aziz, William M. Burke, Nixon Leonardo Cevallos, Linus T. Chuang, Terence J. Colgan, Marcela G. del Carmen, Keiichi Fujiwara, Elise C. Kohn, Jose Enrique Gonzáles Nogales, Thomas Okpoti Konney, Asima Mukhopadhyay, Bishnu D. Paudel, Ićo Tóth, Sarikapan Wilailak, Rahel G. Ghebre Assessment of adult women with ovarian masses and treatment of epithelial ovarian cancer: Asco resource-stratified guideline. JCO Global Oncology. Vol.7, (2021), 1032-1066. doi:10.1200/GO.21.00085 Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/76358

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Title

Assessment of adult women with ovarian masses and treatment of epithelial ovarian cancer: Asco resource-stratified guideline

Author(s)

Verna D. Vanderpuye
 Jean Rene V. Clemenceau
 Sarah Temin
 Zeba Aziz
 William M. Burke
 Nixon Leonardo Cevallos
 Linus T. Chuang
 Terence J. Colgan
 Marcela G. del Carmen
 Keiichi Fujiwara
 Elise C. Kohn
 Jose Enrique Gonzáles Nogales
 Thomas Okpoti Konney
 Asima Mukhopadhyay
 Bishnu D. Paudel
 Ićo Tóth
 Sarikapan Wilailak
 Rahel G. Ghebre

Other Contributor(s)

Ramathibodi Hospital
 Saitama Medical University International Medical Center
 St. Paul‘s Hospital Millennium Medical College
 Komfo Anokye Teaching Hospital
 Bir Hospital
 Massachusetts General Hospital
 Hospital Angeles del Pedregal
 Chittaranjan National Cancer Institute
 National Cancer Institute (NCI)
 University of Minnesota Medical School
 American Society of Clinical Oncology
 Stony Brook University Hospital
 LifeLabs
 Mallow Flower Foundation
 Sociedad Lucha Contra Cancer Ecuador
 Instituto Nacional de Cancerología
 Nuvance Health
 Hameed Latif Hospital
 Korlebu Teaching Hospital
 Northern Gynaecological Oncology Centre

Abstract

PURPOSE To provide expert guidance to clinicians and policymakers in three resource-constrained settings on diagnosis and staging of adult women with ovarian masses and treatment of patients with epithelial ovarian (including fallopian tube and primary peritoneal) cancer. METHODS A multidisciplinary, multinational ASCO Expert Panel reviewed existing guidelines, conducted a modified ADAPTE process, and conducted a formal consensus process with additional experts. RESULTS Existing sets of guidelines from eight guideline developers were found and reviewed for resourceconstrained settings; adapted recommendations from nine guidelines form the evidence base, informing two rounds of formal consensus; and all recommendations received ≥ 75% agreement. RECOMMENDATIONS Evaluation of adult symptomatic women in all settings includes symptom assessment, family history, and ultrasound and cancer antigen 125 serum tumor marker levels where feasible. In limited and enhanced settings, additional imaging may be requested. Diagnosis, staging, and/or treatment involves surgery. Presurgical workup of every suspected ovarian cancer requires a metastatic workup. Only trained clinicians with logistical support should perform surgical staging; treatment requires histologic confirmation; surgical goal is staging disease and performing complete cytoreduction to no gross residual disease. In first-line therapy, platinum-based chemotherapy is recommended; in advanced stages, patients may receive neoadjuvant chemotherapy. After neoadjuvant chemotherapy, all patients should be evaluated for interval debulking surgery. Targeted therapy is not recommended in basic or limited settings. Specialized interventions are resourcedependent, for example, laparoscopy, fertility-sparing surgery, genetic testing, and targeted therapy. Multidisciplinary cancer care and palliative care should be offered. Additional information can be found at www.asco.org/resource-stratified-guidelines. It is ASCO's view that health care providers and health care system decision makers should be guided by the recommendations for the highest stratum of resources available. The guideline is intended to complement but not replace local guidelines.

Keyword(s)

Biochemistry, Genetics and Molecular Biology
 Medicine

Availability

URI

https://repository.li.mahidol.ac.th/handle/20.500.14594/76358

Collections

Scopus 2021