Publication: Levels of stem cell factor and interleukin-3 in serum in acute Plasmodium falciparum malaria
Issued Date
1997-01-01
Resource Type
ISSN
1071412X
Other identifier(s)
2-s2.0-0030893174
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Mahidol University
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SCOPUS
Bibliographic Citation
Clinical and Diagnostic Laboratory Immunology. Vol.4, No.2 (1997), 226-228
Suggested Citation
H. Burgmann, S. Looareesuwan, E. C. Wiesinger, W. Winter, W. Graninger Levels of stem cell factor and interleukin-3 in serum in acute Plasmodium falciparum malaria. Clinical and Diagnostic Laboratory Immunology. Vol.4, No.2 (1997), 226-228. Retrieved from: https://repository.li.mahidol.ac.th/handle/20.500.14594/17920
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Title
Levels of stem cell factor and interleukin-3 in serum in acute Plasmodium falciparum malaria
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Abstract
The purpose of the present study was to measure serum concentrations of stem cell factor (SCF) and interleukin-3 (IL-3) in patients with acute Plasmodium falciparum malaria. Serum samples from 15 patients were taken on day of admission and days 7, 14, 21, and 28. Anemia developed in 80% of patients. A transient increase in IL-3 could be observed at the beginning of the disease. It remains controversial whether the measured concentrations of IL-3 and SCF correlate with the grade of anemia. The possibly suppressed IL-3 and SCF production may contribute to the prolonged anemia in P. falciparum malaria, as has been shown for erythropoietin.